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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Cash flows from operating activities    
Net loss $ (61,999) $ (36,678)
Adjustments to reconcile net loss to net cash used in operating activities    
Depreciation and amortization expense 1,538 1,226
Noncash lease expense 2,529 725
Stock-based compensation expense 12,511 5,263
Loss on disposal of assets for lease 31
Net amortization of premiums and accretion of discounts on investments 10 5
Change in fair value of redeemable convertible preferred stock warrant liability 897
Impairment of in-process research and development 1,190 2,300
Gain on remeasurement of contingent consideration liability (980) (1,900)
Amortization of deferred debt issuance costs 175 134
Changes in operating assets and liabilities:    
Accounts Receivable-related party (30)
Prepaid expenses and other current assets 1,634 (3,233)
Other non-current assets 42 (1,260)
Accounts payable 1,137 (814)
Contract liabilities—related party (9,175) (7,903)
Operating lease liabilities (511) (859)
Accrued and other current liabilities 855 787
Other non-current liabilities (9) (242)
Net cash used in operating activities (51,052) (41,552)
Cash flows from investing activities    
Cash and restricted cash acquired in connection with the Merger 64,114
Proceeds from sales of marketable debt securities 7,500
Purchases of marketable debt securities (5,700)
Proceeds from maturities of marketable debt securities 2,750 57,793
Purchase of property and equipment (13,046) (990)
Net cash provided by (used in) investing activities (2,796) 115,217
Cash flows from financing activities    
Proceeds from issuance of common stock, net of issuance costs 238,129
Proceeds from Employee Stock Purchase Plan 129
Proceeds from exercise of stock options 4,688 460
Deferred issuance costs (261) (157)
Net cash provided by financing activities 242,685 303
Net change in cash, cash equivalents and restricted cash 188,837 73,968
Cash, cash equivalents and restricted cash, at the beginning of the period 88,857 14,889
Cash, cash equivalents and restricted cash, at the end of the period 277,694 88,857
Reconciliation of cash, cash equivalents and restricted cash to consolidated balance sheets:    
Cash and cash equivalents 277,544 84,330
Restricted cash 150 4,527
Cash, cash equivalents and restricted cash, at the end of the period 277,694 88,857
Supplemental cash flow information    
Cash paid for income taxes 43 3
Cash received for income tax refunds 2,766 664
Supplemental disclosures of noncash investing and financing activities    
Purchase of property and equipment included in accounts payable and accrued liabilities 651 115
Common stock offering costs included in accrued liabilities at period end 132
Operating lease right-of-use asset obtained in exchange for operating lease liability 22,367
Conversion of redeemable convertible preferred stock into common stock 114,083
Conversion of redeemable convertible preferred stock warrants to common stock warrants 2,922
Fair value of net assets acquired in Merger 84,142
Adjustment to Goodwill 413 650
Issuance of redeemable convertible preferred stock warrants in connection with the Loan Agreement 144
Topic 842    
Supplemental disclosures of noncash investing and financing activities    
Right-of-use assets recognized upon adoption of Topic 842 $ 1,424