Unaudited Condensed Statements of Cash Flows - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Cash flows from operating activities
Net loss	$ (40,876)	$ (32,066)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	233	87
Stock-based compensation expenses	9,382	3,279
Amortization of premiums and discounts on marketable securities, net	(4,996)
Noncash lease expense	436
Changes in operating assets and liabilities:
Accounts receivable	1,029	(209)
Prepaid expenses and other current assets	(1,328)	388
Accounts payable	464	746
Accrued compensation	(2,779)	(3,762)
Accrued expenses and other current liabilities	(693)	4,071
Deferred revenue	(340)	(1,937)
Operating lease liabilities	(76)	15
Net cash used in operating activities	(39,544)	(29,388)
Cash flows from investing activities
Purchases of property and equipment	(530)	(955)
Proceeds from maturities of short term investments	82,600
Purchases of short term investments	(274,403)
Net cash used in investing activities	(192,333)	(955)
Cash flows from financing activities
Proceeds from sale of common stock in public offerings, gross	53,159
Payment of financing costs	(3,253)	(226)
Proceeds from issuance of common stock upon stock option exercises	2,893	349
Net cash provided by financing activities	52,799	123
Net decrease in cash and cash equivalents	(179,078)	(30,220)
Cash and cash equivalents at beginning of period	292,423	257,254
Cash and cash equivalents cash at end of period	113,345	227,034
Supplemental disclosures
Cash paid for income taxes		4
Right-of-use assets obtained in exchange for lease liabilities		14,597
Supplemental schedule of non-cash investing and financing activities
Vesting of early exercised stock options	5	6
Financing costs incurred, but not paid, included in accrued expenses and accounts payable		339
Costs incurred, but not paid, in connection with capital expenditures included in accounts payable	$ 34	$ 291