Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022
Cash flows from operating activities:
Net loss	$ (47,933)	$ (19,014)
Adjustments to reconcile net loss to net cash provided by (used in)    operating activities:
Depreciation and amortization expense	2,307	691
Stock-based compensation expense	2,832	3,938
Non-cash interest expense related to note payable	2,665	296
Net amortization of premiums and discounts on marketable securities	(211)	276
Gain on disposal of property and equipment	(29)	0
Non-cash operating lease cost	1,911	1,172
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	(13)	(1,660)
Other assets	2	157
Accounts payable	353	(1,128)
Accrued expenses and other current liabilities	(3,397)	(2,395)
Operating lease liability	(1,487)	(1,304)
Net cash used in operating activities	(43,000)	(18,971)
Cash flows from investing activities:
Purchases of property and equipment	0	(146)
Proceeds from sales of property and equipment	3	0
Purchases of marketable securities	(35,568)	(15,690)
Proceeds from sales or maturities of marketable securities	69,070	30,745
Net cash provided by investing activities	33,505	14,909
Cash flows from financing activities:
Payments made on convertible note payable	(28,250)	0
Proceeds from issuance of common stock upon public offering, net	0	22,666
Proceeds from employee stock purchases	77	164
Proceeds from exercise of stock options	5	11
Net cash provided by (used in) financing activities	(28,168)	22,841
Net increase (decrease) in cash and cash equivalents and restricted cash	(37,663)	18,779
Cash and cash equivalents and restricted cash at beginning of period	52,505	57,640
Cash and cash equivalents and restricted cash at end of period	14,842	76,419
Supplemental disclosure of cash flow information:
Cash paid for interest	1,666	1,097
Supplemental disclosure of non-cash investing and financing activities:
Re-measurement of right-of-use asset and related lease liability	(19,477)	755
Purchases of property and equipment included in accounts payable and accrued expenses	$ 0	$ 92