Nature of the Business - Additional Information (Details) - USD ($)				3 Months Ended			6 Months Ended		23 Months Ended
	Sep. 15, 2023	Jun. 15, 2023	Aug. 05, 2021	Sep. 15, 2023	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Dec. 31, 2022
Class of Stock [Line Items]
Common stock, par value (in dollars per share)		$ 0.0001			$ 0.0001		$ 0.0001		$ 0.0001	$ 0.0001
Exchange ratio, quotient numerator		$ 40,000,000
Share price (in dollars per share)		$ 5.2831
Period following the closing		10 years
Minimum cash amount		$ 19,600,000
Termination agreement lease amount		$ 1,595,000
Accumulated deficit					$ 252,262,000		$ 252,262,000		$ 252,262,000	$ 204,329,000
June Reduction In Force
Class of Stock [Line Items]
Restructuring workforce reduced percentage		50.00%
Forecast
Class of Stock [Line Items]
Termination agreement lease amount	$ 8,405,000			$ 10,000,000
SRF114
Class of Stock [Line Items]
Upfront payment percentage		25.00%
SRF388
Class of Stock [Line Items]
Upfront payment percentage		50.00%
GSK Agreement
Class of Stock [Line Items]
Milestone and royalty-based payment percentage		70.00%
Novartis Collaboration
Class of Stock [Line Items]
Milestone and royalty-based payment percentage		70.00%
2021 ATM Facility
Class of Stock [Line Items]
Number of shares issued (in shares)					0	1,025,935	0	8,363,186	14,611,756
Net proceeds from issuance of common stock						$ 2,110,000		$ 22,666,000	$ 41,421,000
2021 ATM Facility | Maximum
Class of Stock [Line Items]
Gross proceeds from issuance of common stock			$ 80,000,000
Percentage of gross proceeds of shares sold for compensation (as a percent)			3.00%