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- Definition

Contract with Customer, Liability, Additional Payments to be Received

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- Definition

Contract With Customer, Transaction Price

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- Definition

Contract with Customer, Upfront Payment

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- Definition

Potential milestones payment.

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- Definition

Revenue, Number of Performance Obligations

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- Definition

Revenue, Performance Obligation, Number of Targets

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- Definition

Revenue, Performance Obligation, Number of Targets Purchased

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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- Definition

Amount of revenue from collaborative arrangement. Excludes revenue from contract with customer under Topic 606.

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- Definition

Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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Collaboration and License Agreements - Additional Information (Details)	1 Months Ended	3 Months Ended		6 Months Ended		12 Months Ended
	Jan. 31, 2016 target	Jun. 30, 2022 USD ($)	Jun. 30, 2021 USD ($)	Jun. 30, 2022 USD ($) obligation	Jun. 30, 2021 USD ($)	Dec. 31, 2020 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
License related revenue		$ 0	$ 515,000	$ 30,000,000	$ 2,141,000
GSK Agreement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Contract with customer, expiration period				10 years
Number of performance obligations \| obligation				3
Transaction price		90,264,000		$ 90,264,000
GSK Agreement \| License
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
License related revenue		0	515,000	30,000,000	2,141,000
GSK Agreement \| License \| Transferred at Point in Time
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Upfront payment		85,000,000		85,000,000
License related revenue						$ 85,000,000
GSK Agreement \| License \| Transferred over Time
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Additional payments to be received		4,314,000		4,314,000
GSK Agreement \| Transition Services
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
License related revenue		0	299,000		661,000
GSK Agreement \| Transition Services \| Transferred over Time
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Additional payments to be received		950,000		950,000
GSK Agreement \| Supply Services
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
License related revenue			216,000	0	1,480,000
GSK Agreement \| Clinical Milestone Payment
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestones payment				60,000,000
GSK Agreement \| Regulatory Milestone Payment
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestones payment				155,000,000
GSK Agreement \| Sales Milestone Payment
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestones payment				485,000,000
Novartis Collaboration
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Number of option targets \| target	4
Number of option targets purchased \| target	3
Novartis Collaboration \| Novartis Institutes for Biomedical Research, Inc.
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue		$ 0	$ 0	0	$ 0
Novartis Collaboration \| Novartis Institutes for Biomedical Research, Inc. \| Development Milestone
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestones payment				325,000,000
Novartis Collaboration \| Novartis Institutes for Biomedical Research, Inc. \| Sales Milestone
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Potential milestones payment				$ 200,000,000