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Stock-Based Awards (Tables)
 6 Months Ended
Jun. 30, 2022
Share-Based Payment Arrangement [Abstract]  
Summary of Stock Option Activity
The following table summarizes the Company’s stock option activity since December 31, 2021:
 
 Number of
Shares		Weighted
Average
Exercise
Price		Weighted
Average
Remaining
Contractual
Term		Aggregate
Intrinsic
Value
   (in years) 
Outstanding as of December 31, 20217,057,258 $6.59 6.98$4,678 
Granted2,040,900 3.50 
Exercised(9,343)1.18 
Forfeited(412,284)7.13 
Outstanding as of June 30, 20228,676,531 $5.84 7.26$474 
Options exercisable at June 30, 20225,179,174 $6.20 6.05$472 
Vested and expected to vest at June 30, 20228,676,531 $5.84 7.26$474 
The following table summarizes the Company’s stock option under the Inducement Plan activity since December 31, 2021:

Number of
Shares		Weighted
Average
Exercise
Price		Weighted
Average
Remaining
Contractual
Term		Aggregate
Intrinsic
Value
(in years)
Outstanding as of December 31, 2021— $— 0.00$— 
Granted291,600 2.94 
Exercised— — 
Forfeited— — 
Outstanding as of June 30, 2022291,600 $2.94 9.75$— 
Options exercisable at June 30, 2022— $— 0.00$— 
Vested and expected to vest at June 30, 2022291,600 $2.94 9.75$— 
Summary of Restricted Stock Unit Activity
The table below summarizes the Company’s RSU activity since December 31, 2021:
 
 Number of
Shares		Weighted
Average
Grant-Date
Fair Value
Unvested restricted stock units as of December 31, 2021— $— 
Granted732,000 3.64 
Vested— — 
Forfeited(21,000)3.64 
Unvested restricted stock units as of June 30, 2022711,000 $3.64 
Summary of Stock-Based Compensation Expense Related to Stock Options and Restricted Stock Awards
The Company recorded stock-based compensation expense related to stock options and restricted stock unit awards in the following expense categories of its condensed consolidated statements of operations and comprehensive income (loss):
 
 Three months ended June 30,Six months ended June 30,
 2022202120222021
Research and development expenses$777 $898 $1,360 $1,687 
General and administrative expenses1,296 1,381 2,578 2,972 
 $2,073 $2,279 $3,938 $4,659