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Leases - Additional Information (Details)
$ in Thousands
1 Months Ended 12 Months Ended
May 30, 2018
ft²
Dec. 31, 2019
USD ($)
Dec. 31, 2018
USD ($)
Dec. 31, 2017
USD ($)
Dec. 31, 2020
Jan. 01, 2019
USD ($)
Lease Agreements [Line Items]            
Cash paid for lease liabilities   $ 4,148        
Total rent expense     $ 1,649 $ 1,194    
Office and Laboratory Space | CoStim Pharmaceuticals, Inc            
Lease Agreements [Line Items]            
Operating sublease, expiration period   2018-03        
Sublease payments received from third-party tenant     $ 231 $ 305    
Massachusetts            
Lease Agreements [Line Items]            
Lease term   10 years        
Renewal terms of lease   5 years        
Operating lease, expiration period   2027-02        
Lease commenced period   2017-04        
Operting lease, incentives           $ 4,803
Massachusetts | Sublease agreement with EQRx | Office Space            
Lease Agreements [Line Items]            
Sublease commenced date   Jan. 01, 2020        
Massachusetts | Sublease agreement with EQRx | Office Space | Scenario, Forecast            
Lease Agreements [Line Items]            
Lease term         3 years  
Massachusetts | Lease Amendment            
Lease Agreements [Line Items]            
Lease term 10 years          
Lease term, description In May 2018, the Company executed an amendment to lease an additional 33,526 square feet at 50 Hampshire Street in Cambridge, Massachusetts, with a 10-year term. This additional space became available for occupancy on January 1, 2020          
Land subject to additional ground leases | ft² 33,526          
Massachusetts | Lease Amendment | Sublease agreement with EQRx            
Lease Agreements [Line Items]            
Lease term 10 years          
Lease term, description In May 2018, the Company executed an amendment to lease an additional 33,526 square feet at 50 Hampshire Street in Cambridge, Massachusetts, with a 10-year term.          
Land subject to additional ground leases | ft² 33,526          
Massachusetts | Minimum            
Lease Agreements [Line Items]            
Lease term   1 year        
Operating lease, discount rate   950.00%        
Massachusetts | Maximum            
Lease Agreements [Line Items]            
Lease term   10 years        
Operating lease, discount rate   1050.00%