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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Statement Of Income And Comprehensive Income [Abstract]      
Collaboration revenue - related party $ 15,360 $ 59,417 $ 12,826
Type of Revenue [Extensible List] us-gaap:CollaborativeArrangementMember us-gaap:CollaborativeArrangementMember us-gaap:CollaborativeArrangementMember
Operating expenses:      
Research and development $ 52,118 $ 52,492 $ 47,783
General and administrative 20,608 16,076 11,033
Total operating expenses 72,726 68,568 58,816
Loss from operations (57,366) (9,151) (45,990)
Interest and other income, net 2,577 2,554 613
Net loss (54,789) (6,597) (45,377)
Accretion of redeemable convertible preferred stock to redemption value   (11) (40)
Net loss attributable to common stockholders $ (54,789) $ (6,608) $ (45,417)
Net loss per share attributable to common stockholders—basic and diluted $ (1.97) $ (0.33) $ (18.35)
Weighted average common shares outstanding—basic and diluted 27,854,912 19,990,773 2,474,800
Comprehensive loss:      
Net loss $ (54,789) $ (6,597) $ (45,377)
Other comprehensive loss:      
Unrealized gain on marketable securities, net of tax 222 127 107
Comprehensive loss $ (54,567) $ (6,470) $ (45,270)