X0306 4 2022-03-01 0 0001718108 Surface Oncology, Inc. SURF 0001283882 ONEILL ALISON C/O SURFACE ONCOLOGY, INC. 50 HAMPSHIRE STREET, 8TH FLOOR CAMBRIDGE MA 02139 0 1 0 0 Chief Medical Officer Common Stock 2022-03-01 4 A 0 38000 0.00 A 68191 D Stock Option (Right to Buy) 3.64 2022-03-01 4 A 0 108000 0.00 A 2032-03-01 Common Stock 108000 108000 D The shares were acquired pursuant to a restricted stock unit award under the 2018 Stock Option and Incentive Plan. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The restricted stock units vest as follows: 40% on August 1, 2022 and the remaining 60% on August 1, 2023, so long as the reporting person remains an employee or other service provider of the Issuer on such date. The option vests in equal monthly installments over four years, so that all of the underlying shares shall be vested on February 8, 2026, so long as the reporting person remains an employee or other service provider of the Issuer on such dates. /s/ Jessica Fees, as Attorney-in-Fact 2022-03-03