X0306 4 2020-03-01 0 0001718108 Surface Oncology, Inc. SURF 0001283882 ONEILL ALISON C/O SURFACE ONCOLOGY, INC. 50 HAMPSHIRE STREET, 8TH FLOOR CAMBRIDGE MA 02139 0 1 0 0 Chief Medical Officer Common Stock 2020-03-01 4 A 0 45000 0.00 A 45000 D Common Stock 2021-07-21 4 S 0 14809 6.10 D 30191 D The shares were acquired pursuant to a restricted stock unit award under the 2018 Stock Option and Incentive Plan. Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The restricted stock units vest in full on the date 18 months after January 21, 2020, so long as the reporting person remains an employee or other service provider of the Company on such date. Amount reported represents the number of shares sold by the reporting person to cover the tax withholding obligations in connection with the vesting of restricted stock units. /s/ Jessica Fees, as Attorney-in-Fact 2022-01-14