A summary of the activity and related data by award type under the 2018 Equity Incentive Plan and the 2020 Inducement Equity Incentive Plan (collectively, the “Plans”) for the six months ended June 30, 2022 is set forth below:

	Stock Options			Weighted Average Exercise Price		Weighted Average Remaining Life (in years)		Aggregate Intrinsic Value (in thousands)
Outstanding at December 31, 2021		108,448		$	345.54
Canceled/forfeited		(6,871	)	$	90.76
Outstanding at June 30, 2022		101,577		$	362.77		3.83	$	—
Exercisable at June 30, 2022		88,451		$	412.48		3.27	$	—
Vested and expected to vest at June 30, 2022		101,577		$	362.77		3.83	$	—

	Restricted Stock Units			Weighted Average Grant Date Fair Value
Outstanding at December 31, 2021		70,025		$	4.37
Vested		(5,864	)	$	12.17
Canceled/forfeited		(57,343	)	$	3.04
Outstanding at June 30, 2022		6,818		$	8.88

	Restricted Stock Awards			Weighted Average Grant Date Fair Value
Outstanding at December 31, 2021		179,334		$	4.71
Vested		(63,284	)	$	4.78
Canceled/forfeited		(36,062	)	$	4.31
Outstanding at June 30, 2022		79,988

The following table summarizes stock-based compensation expense for the Plans included in operating expenses for the periods presented (in thousands):

	Three Months Ended June 30,				Six Months Ended June 30,
	2022		2021		2022		2021
Selling, general and administrative	$	104	$	530	$	217	$	1,473
Research and development		19		95		68		224
Stock-based compensation in operating expenses	$	123	$	625	$	285	$	1,697

Stock-based compensation expense of approximately $3,000 and $27,000 was capitalized to inventory and property and equipment during the three months ended June 30, 2022 and 2021, respectively. Stock-based compensation expense of approximately $6,000 and $67,000 was capitalized to inventory and property and equipment during the six months ended June 30, 2022 and 2021, respectively.

Unrecognized stock-based compensation expense by award type and the remaining weighted average recognition period over which such expense is expected to be recognized as of June 30, 2022 was as follows:

	Unrecognized Expense (in thousands)		Remaining Weighted Average Recognition Period (in years)
Stock options	$	190		1.5
Restricted stock awards	$	321		1.7
Restricted stock units	$	50		1.4