Note 13 - Stock-based Compensation - Schedule of Stock Option Activity (Details) - USD ($)	9 Months Ended	12 Months Ended
	Sep. 30, 2025	Dec. 31, 2024
Share-Based Payment Arrangement, Option [Member]
Options, Outstanding (in shares)	3,701
Options, outstanding, weighted average exercise price (in dollars per share)	$ 88.72
Options, outstanding, weighted average remaining life (Year)	9 years 6 months	8 years 4 months 17 days
Options, outstanding, aggregate intrinsic value	$ 0	$ 0
Options exercised (in shares)	0
Options exercised, weighted average exercise price (in dollars per share)	$ 0
Options granted (in shares)	160,360
Options granted, weighted average exercise price (in dollars per share)	$ 6.34
Cancelled/forfeited (in shares)	(26,021)
Cancelled/forfeited, weighted average exercise price (in dollars per share)	$ 8.82
Options, outstanding (in shares)	138,040	3,701
Options, outstanding, weighted average exercise price (in dollars per share)	$ 8.08	$ 88.72
Options, outstanding, vested and expected to vest (in shares)	138,040
Options, outstanding, vested and expected to vest, weighted average exercise price (in dollars per share)	$ 8.08
Options, outstanding, vested and expected to vest, weighted average remaining life (Year)	9 years 6 months
Options, outstanding, vested and expected to vest, aggregate intrinsic value	$ 0
Options, exercisable, vested and expected to vest (in shares)	13,573
Options, exercisable, vested and expected to vest, weighted average exercise price (in dollars per share)	$ 17.71
Options, exercisable, vested and expected to vest, weighted average remaining life (Year)	8 years 7 months 20 days
Options, exercisable, vested and expected to vest, aggregate intrinsic value	$ 0
Non-plan Options [Member]
Options, Outstanding (in shares)	1,315
Options, outstanding, weighted average exercise price (in dollars per share)	$ 101.1
Options, outstanding, weighted average remaining life (Year)	9 years 3 months 7 days	9 years 3 months 29 days
Options, outstanding, aggregate intrinsic value	$ 0	$ 0
Options exercised (in shares)	0
Options exercised, weighted average exercise price (in dollars per share)	$ 0
Options granted (in shares)	26,315
Options granted, weighted average exercise price (in dollars per share)	$ 10.07
Cancelled/forfeited (in shares)	(1,315)
Cancelled/forfeited, weighted average exercise price (in dollars per share)	$ 101.1
Options, outstanding (in shares)	26,315	1,315
Options, outstanding, weighted average exercise price (in dollars per share)	$ 10.07	$ 101.1
Options, outstanding, vested and expected to vest (in shares)	26,315
Options, outstanding, vested and expected to vest, weighted average exercise price (in dollars per share)	$ 10.07
Options, outstanding, vested and expected to vest, aggregate intrinsic value	$ 0
Options, exercisable, vested and expected to vest (in shares)	5,847
Options, exercisable, vested and expected to vest, weighted average exercise price (in dollars per share)	$ 10.07
Options, exercisable, vested and expected to vest, weighted average remaining life (Year)	9 years 3 months 7 days
Options, exercisable, vested and expected to vest, aggregate intrinsic value	$ 0
Options, Exercisable, weighted average remaining life (Year)	9 years 3 months 7 days