Note 2 - Summary of Significant Accounting Policies - Segment Reporting (Details) - USD ($) $ in Thousands		3 Months Ended						9 Months Ended
		Sep. 30, 2025	Jun. 30, 2025	Mar. 31, 2025	Sep. 30, 2024	Jun. 30, 2024	Mar. 31, 2024	Sep. 30, 2025	Sep. 30, 2024
Revenues		$ 226			$ 96			$ 581	$ 271
Cost of revenues		18			10			43	31
Acquired in-process research and development		0			0			1,967	0
Research and development expense		276			63			534	181
Interest income		(10)			(7)			(31)	(47)
Change in fair value of royalties payable due to related parties		(726)			1,233			2,104	2,823
Income tax benefit		78			(0)			(1,596)	(0)
Segment net loss		(2,344)	$ (5,458)	$ (4,045)	(4,120)	$ (4,220)	$ (2,675)	(11,847)	(11,015)
Operating Segments [Member]
Revenues		226			96			581	271
Cost of revenues		18			10			43	31
Acquired in-process research and development		0			0			1,967	0
Depreciation and amortization expense		528			530			1,588	1,578
Stock-based compensation expense		70			17			259	36
Salaries and benefits expense		1,027			1,236			3,651	2,957
Professional fees		582			373			1,626	1,419
Research and development expense		276			63			534	181
Interest income		(10)			(7)			(31)	(47)
Interest expense		83			32			199	40
Change in fair value of royalties payable due to related parties		(726)			1,233			2,104	2,823
Change in fair value of trading debt securities		(107)			0			(117)	0
Income tax benefit		78			0			(1,596)	0
Other segment items (1)	[1]	751			729			2,201	2,268
Segment net loss		(2,344)			(4,120)			(11,847)	(11,015)
Segment Reporting, Reconciling Item, Excluding Corporate Nonsegment [Member]
Segment net loss		$ 0			$ 0			$ 0	$ 0

[1] Other segment items include other expenses, net, consulting fees, investor relations and SEC fees, insurance fees, and other selling, general, and administrative expenses. Other selling, general, and administrative expenses primarily consist of travel expenses, computer and information technology expenses, and rent expenses.