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Note 13 - Stock-based Compensation - Schedule of Stock Option Activity (Details) - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2025
Dec. 31, 2024
Share-Based Payment Arrangement, Option [Member]    
Options, Outstanding (in shares) 70,605  
Options, outstanding, weighted average exercise price (in dollars per share) $ 20.88  
Options, outstanding, weighted average remaining life (Year) 9 years 9 months 3 days 8 years 4 months 17 days
Options, outstanding, aggregate intrinsic value $ 0 $ 0
Options exercised (in shares) 0  
Options exercised, weighted average exercise price (in dollars per share) $ 0  
Options granted (in shares) 1,627,500  
Options granted, weighted average exercise price (in dollars per share) $ 0.42  
Cancelled/forfeited (in shares) (56,921)  
Cancelled/forfeited, weighted average exercise price (in dollars per share) $ 0.65  
Options, outstanding (in shares) 1,641,184 70,605
Options, outstanding, weighted average exercise price (in dollars per share) $ 1.29 $ 20.88
Options, outstanding, vested and expected to vest (in shares) 1,641,184  
Options, outstanding, vested and expected to vest, weighted average exercise price (in dollars per share) $ 1.29  
Options, outstanding, vested and expected to vest, weighted average remaining life (Year) 9 years 9 months 3 days  
Options, outstanding, vested and expected to vest, aggregate intrinsic value $ 0  
Options, exercisable, vested and expected to vest (in shares) 278,288  
Options, exercisable, vested and expected to vest, weighted average exercise price (in dollars per share) $ 4.95  
Options, exercisable, vested and expected to vest, weighted average remaining life (Year) 9 years 6 months 21 days  
Options, exercisable, vested and expected to vest, aggregate intrinsic value $ 0  
Non-plan Options [Member]    
Options, Outstanding (in shares) 25,000  
Options, outstanding, weighted average exercise price (in dollars per share) $ 5.32  
Options, outstanding, weighted average remaining life (Year) 9 years 8 months 26 days 9 years 3 months 29 days
Options, outstanding, aggregate intrinsic value $ 0 $ 0
Options exercised (in shares) 0  
Options exercised, weighted average exercise price (in dollars per share) $ 0  
Options granted (in shares) 500,000  
Options granted, weighted average exercise price (in dollars per share) $ 0.53  
Cancelled/forfeited (in shares) 0  
Cancelled/forfeited, weighted average exercise price (in dollars per share) $ 0  
Options, outstanding (in shares) 525,000 25,000
Options, outstanding, weighted average exercise price (in dollars per share) $ 0.76 $ 5.32
Options, outstanding, vested and expected to vest (in shares) 525,000  
Options, outstanding, vested and expected to vest, weighted average exercise price (in dollars per share) $ 0.76  
Options, outstanding, vested and expected to vest, aggregate intrinsic value $ 0  
Options, exercisable, vested and expected to vest (in shares) 27,778  
Options, exercisable, vested and expected to vest, weighted average exercise price (in dollars per share) $ 0.53  
Options, exercisable, vested and expected to vest, weighted average remaining life (Year) 9 years 8 months 26 days  
Options, exercisable, vested and expected to vest, aggregate intrinsic value $ 0  
Options, Exercisable, weighted average remaining life (Year) 9 years 9 months 7 days