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Note 15 - Stock-based Compensation - Schedule of Stock Option Activity (Details) - USD ($)
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Share-Based Payment Arrangement, Option [Member]    
Options, Outstanding (in shares) 21,465  
Options, outstanding, weighted average exercise price (in dollars per share) $ 64.71  
Options, outstanding, weighted average remaining life (Year) 8 years 4 months 17 days 6 years 4 months 17 days
Options, outstanding, aggregate intrinsic value $ 0 $ 0
Options exercised (in shares) 0  
Options exercised, weighted average exercise price (in dollars per share) $ 0  
Options granted (in shares) 66,000  
Options granted, weighted average exercise price (in dollars per share) $ 4.08  
Cancelled/forfeited (in shares) (16,860)  
Cancelled/forfeited, weighted average exercise price (in dollars per share) $ 4.49  
Options, outstanding (in shares) 70,605 21,465
Options, outstanding, weighted average exercise price (in dollars per share) $ 20.88 $ 64.71
Options, outstanding, vested and expected to vest (in shares) 70,605  
Options, outstanding, vested and expected to vest, weighted average exercise price (in dollars per share) $ 20.88  
Options, outstanding, vested and expected to vest, weighted average remaining life (Year) 8 years 4 months 17 days  
Options, outstanding, vested and expected to vest, aggregate intrinsic value $ 0  
Options, exercisable, vested and expected to vest (in shares) 18,352  
Options, exercisable, vested and expected to vest, weighted average exercise price (in dollars per share) $ 68.64  
Options, exercisable, vested and expected to vest, weighted average remaining life (Year) 5 years 11 months 15 days  
Options, exercisable, vested and expected to vest, aggregate intrinsic value $ 0  
Non-plan Options [Member]    
Options, Outstanding (in shares) 0  
Options, outstanding, weighted average exercise price (in dollars per share) $ 0  
Options, outstanding, weighted average remaining life (Year) 9 years 3 months 29 days  
Options, outstanding, aggregate intrinsic value $ 0 $ 0
Options exercised (in shares) 0  
Options exercised, weighted average exercise price (in dollars per share) $ 0  
Options granted (in shares) 25,000  
Options granted, weighted average exercise price (in dollars per share) $ 5.32  
Cancelled/forfeited (in shares) 0  
Cancelled/forfeited, weighted average exercise price (in dollars per share) $ 0  
Options, outstanding (in shares) 25,000 0
Options, outstanding, weighted average exercise price (in dollars per share) $ 5.32 $ 0
Options, outstanding, vested and expected to vest (in shares) 25,000  
Options, outstanding, vested and expected to vest, weighted average exercise price (in dollars per share) $ 5.32  
Options, outstanding, vested and expected to vest, weighted average remaining life (Year) 9 years 3 months 29 days  
Options, outstanding, vested and expected to vest, aggregate intrinsic value $ 0  
Options, exercisable, vested and expected to vest (in shares) 0  
Options, exercisable, vested and expected to vest, weighted average exercise price (in dollars per share) $ 0  
Options, exercisable, vested and expected to vest, aggregate intrinsic value $ 0