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Aggregate number of common shares reserved for future issuance.

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Amount of cost to be recognized for option under share-based payment arrangement.

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Amount of noncash expense for share-based payment arrangement.

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Description of service or performance condition required to be met for earning right to award under share-based payment arrangement. Includes, but is not limited to, combination of market, performance or service condition.

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Weighted average remaining contractual term for equity-based awards excluding options, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Date the equity-based award expires, in CCYY-MM-DD format.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Number of shares authorized for issuance under share-based payment arrangement.

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The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable.

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The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan.

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Gross number of share options (or share units) granted during the period.

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Maximum number of shares that may be issued in accordance with the plan as a proportion of outstanding capital stock.

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Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options.

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Percentage of vesting of award under share-based payment arrangement.

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Weighted average remaining contractual term for option awards outstanding, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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Number of shares issued during the period as a result of an employee stock purchase plan.

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Total number of shares issued during the period, including shares forfeited, as a result of Restricted Stock Awards.

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Aggregate change in value for stock issued during the period as a result of employee stock purchase plan.

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Stock-Based Compensation - Additional Information (Details) - USD ($)		1 Months Ended	3 Months Ended		9 Months Ended		12 Months Ended
	Jun. 04, 2018	Sep. 30, 2018	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020	Dec. 31, 2020	Dec. 31, 2019	Dec. 31, 2018	Mar. 13, 2020	Jun. 08, 2018
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock-based compensation					$ 1,967,000	$ 3,044,000	$ 4,082,000	$ 23,543,000
Weighted Average Remaining Life (in years)					1 year 10 months 24 days
2018 Stock Compensation Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock reserve for issuance	132,000	132,000					65,285
Maximum annual increase of outstanding stock reserved for future issuance, Percentage							5.00%
Number of shares available for grant under the plan							110,329
2020 Inducement Equity Incentive Plan (the "2020 plan") [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock reserve for issuance										32,000
Number of shares granted under the plan							18,000
Weighted average exercise price of stock options							$ 25.50
Number of shares exercisable under the plan							3,375
2018 Employee Stock Purchase Plan (ESPP) [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Common stock reserve for issuance							11,870
Maximum annual increase of outstanding stock reserved for future issuance, Percentage							1.25%
Number of shares available for grant under the plan							19,463
Common stock discount rate							85.00%
Shares issued under employee stock purchase plan, Shares							5,278	368
Shares issued under employee stock purchase plan, Value							$ 42,000,000	$ 37,000,000
Stock Options [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock-based compensation			$ 5,000,000	$ 48,000,000	$ 100	$ 100	200,000	$ 1,000,000.0
Unrecognized compensation expense for stock options issued			$ 400		$ 400		$ 1,800,000
Weighted Average Remaining Life (in years)					4 years 9 months 25 days		6 years 5 months 1 day	9 years 5 months 4 days	9 years 5 months 4 days
Weighted-average recognized period							1 year 2 months 12 days
Number of shares granted under the plan							11,729	60,854
Weighted average exercise price of stock options							$ 30.69	$ 30.50
Number of shares exercisable under the plan			95,096		95,096		84,376
Stock Options [Member] \| 2018 Stock Compensation Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Authorized replacement equity awards of stock options and restricted stock units	76,076
Share-based compensation arrangement by share-based payment award, Award vesting rights	generally vest 33% on the first anniversary of the grant date with the balance vesting monthly over the remaining two years
Share based compensation awards expiration date		Jan. 31, 2020
Stock Options [Member] \| 2018 Stock Compensation Plan [Member] \| First Anniversary [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock options granted under the 2018 Plan vesting percentage	33.00%	25.00%
Stock Options [Member] \| 2018 Stock Compensation Plan [Member] \| Second Anniversary [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock options granted under the 2018 Plan vesting percentage		25.00%
Stock Options [Member] \| 2018 Stock Compensation Plan [Member] \| Third Anniversary [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock options granted under the 2018 Plan vesting percentage		25.00%
Stock Options [Member] \| 2018 Stock Compensation Plan [Member] \| Forth Anniversary [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Stock options granted under the 2018 Plan vesting percentage		25.00%
Restricted Stock Units (RSUs) [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Unrecognized compensation expense for stock options issued			$ 300		$ 300		$ 600,000
Weighted-average recognized period					2 years		1 year 10 months 24 days
Restricted Stock Units (RSUs) [Member] \| 2018 Stock Compensation Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Authorized replacement equity awards of stock options and restricted stock units											53,633
Restricted Stock Awards (RSAs) [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Unrecognized compensation expense for stock options issued			$ 800		$ 800
Weighted-average recognized period					2 years 4 months 24 days
Restricted Stock Awards (RSAs) [Member] \| 2020 Inducement Equity Incentive Plan (the "2020 plan") [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Restricted stock awards granted							5,000
Restricted stock awards with grant date fair value							$ 100,000
Restricted Stock [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Unrecognized compensation expense for stock options issued							$ 1,400,000
Weighted-average recognized period							2 years 9 months 18 days