Condensed Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Mar. 31, 2026	Dec. 31, 2025
Current assets:
Cash and cash equivalents	$ 387,626	$ 205,326
Short-term marketable securities	600,058	662,553
Prepaid expenses and other current assets	35,068	32,779
Total current assets	1,022,752	900,658
Long-term marketable securities	63,785	98,322
Property and equipment, net	51,728	52,402
Finance lease right-of-use asset	47,616	48,531
Operating lease right-of-use asset	17,922	19,002
Intangible asset, net	36,000	0
Other non-current assets	26,220	25,939
Total assets	1,266,023	1,144,854
Current liabilities:
Accounts payable	40,380	505
Other accrued costs and current liabilities	69,776	97,846
Total current liabilities	110,156	98,351
Operating lease liability, less current portion	24,680	27,210
Finance lease liability, less current portion	5,508	5,532
Liability related to the revenue participation right agreement	199,581	0
Total liabilities	339,925	131,093
Commitments and contingencies (Note 9)
Stockholders' equity:
Convertible preferred stock, $0.01 par value; 40,000,000 shares authorized as of March 31, 2026 and December 31, 2025; 0 shares issued and outstanding as of March 31, 2026 and December 31, 2025	0	0
Common stock, $0.01 par value; 400,000,000 shares authorized as of March 31, 2026 and December 31, 2025; 158,656,318 shares and 156,182,177 shares issued and outstanding as of March 31, 2026 and December 31, 2025, respectively	1,913	1,888
Additional paid-in capital	3,104,838	3,062,715
Accumulated other comprehensive income (loss)	(682)	682
Accumulated deficit	(2,179,971)	(2,051,524)
Total stockholders' equity	926,098	1,013,761
Total liabilities and stockholders’ equity	$ 1,266,023	$ 1,144,854