Commitments and Contingencies - Narrative (Details)	1 Months Ended	12 Months Ended
	May 31, 2018 USD ($) ft²	Dec. 31, 2023 USD ($)	Dec. 31, 2025 USD ($)	Dec. 04, 2025 USD ($)	Dec. 31, 2024 USD ($)	Apr. 30, 2023 USD ($) ft²
Loss Contingencies [Line Items]
Finance lease right-of-use asset			$ 48,531,000		$ 47,533,000
Purchase commitments			44,300,000		60,800,000
Other Commitment			1,500,000		$ 2,200,000
Royalty Pharma | Royalty Agreement
Loss Contingencies [Line Items]
Authorized funding				$ 275,000,000.0
Royalty rate				9.25%
Initial payment				$ 200,000,000.0
Additional payment				$ 75,000,000.0
Initial investment proceeds multiple, maximum				3.0
Initial investment proceeds multiple, minimum				2.5
Royalty funding arrangement liability			0
Headquarters Lease
Loss Contingencies [Line Items]
Area under lease | ft²	148,020
Lease period	10 years
Lease renewal option term	10 years
Headquarters Lease | Landlord Funded Tenant Improvements
Loss Contingencies [Line Items]
Tenant improvement allowance repayable in rent	$ 4,400,000
Headquarters Lease | Maximum | Landlord Funded Tenant Improvements
Loss Contingencies [Line Items]
Leasehold improvements	$ 25,900,000
Operating Lease, 9.3 Year Lease Agreement, Terminated | SLC Lease | Building
Loss Contingencies [Line Items]
Accelerated depreciation on leasehold improvements in relation to SLC Lease termination		$ 7,900,000
Finance Lease, 15 Year Lease Agreement | New SLC Finance Lease | Laboratory, Office, and Warehouse
Loss Contingencies [Line Items]
Lease not yet commenced, area under lease | ft²						59,336
Lease not yet commenced, period						15 years
Lease not yet commenced, undiscounted lease payments						$ 13,400,000
Finance lease renewal option term						10 years
Finance Lease, 15 Year Lease Agreement | New SLC Finance Lease | Landlord Owned Assets
Loss Contingencies [Line Items]
Finance lease right-of-use asset			$ 47,400,000