Stock-Based Awards - Summary of Stock-Based Compensation Expense (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2024	Sep. 30, 2023	Sep. 30, 2024	Sep. 30, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total	$ 24,860	$ 27,459	$ 77,800	$ 82,114
Research and development
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total	14,141	15,821	44,847	47,795
General and administrative
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total	$ 10,719	$ 11,638	$ 32,953	$ 34,319