Stock-Based Awards - Summary of Stock-Based Compensation Expense (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023	Jun. 30, 2024	Jun. 30, 2023
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total	$ 25,100	$ 26,570	$ 52,940	$ 54,654
Research and development
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total	14,364	15,189	30,706	31,973
General and administrative
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Total	$ 10,736	$ 11,381	$ 22,234	$ 22,681