Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Loss	Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2022		135,965,918
Beginning balance at Dec. 31, 2022	$ 1,042,430	$ 1,686	$ 2,018,617	$ (6,886)	$ (970,987)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuances under equity incentive plans (in shares)		204,308
Issuances under equity incentive plans	1,604	$ 2	1,602
Vesting of restricted stock units (in shares)		571,401
Vesting of restricted stock units	0	$ 6	(6)
Stock-based compensation	28,084		28,084
Net loss	(109,781)				(109,781)
Other comprehensive income (loss)	4,369			4,369
Ending balance (in shares) at Mar. 31, 2023		136,741,627
Ending balance at Mar. 31, 2023	$ 966,706	$ 1,694	2,048,297	(2,517)	(1,080,768)
Beginning balance (in shares) at Dec. 31, 2023	138,385,498	138,385,498
Beginning balance at Dec. 31, 2023	$ 1,030,954	$ 1,711	2,144,811	643	(1,116,211)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuances under equity incentive plans (in shares)		130,214
Issuances under equity incentive plans	1,022	$ 1	1,021
Issuance of common stock and pre-funded warrants, net of issuance costs of $480K (in shares)		3,244,689
Issuance of common stock and pre-funded warrants, net of issuance costs of $480K	499,253	$ 32	499,221
Vesting of restricted stock units (in shares)		752,455
Vesting of restricted stock units	0	$ 7	(7)
Stock-based compensation	27,987		27,987
Net loss	(101,802)				(101,802)
Other comprehensive income (loss)	$ (1,939)			(1,939)
Ending balance (in shares) at Mar. 31, 2024	142,512,856	142,512,856
Ending balance at Mar. 31, 2024	$ 1,455,475	$ 1,751	$ 2,673,033	$ (1,296)	$ (1,218,013)