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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Collaboration revenue:    
Collaboration revenue from customers [1] $ 0 $ 35,141
Total collaboration revenue 0 35,141
Operating expenses:    
Research and development [2] 107,016 128,816
General and administrative 25,236 27,140
Total operating expenses 132,252 155,956
Gain from divestiture of small molecule programs 14,537 0
Loss from operations (117,715) (120,815)
Interest and other income, net 15,913 11,034
Net loss (101,802) (109,781)
Other comprehensive income (loss):    
Net unrealized gain (loss) on marketable securities, net of tax (1,939) 4,369
Comprehensive loss $ (103,741) $ (105,412)
Net loss per share, basic (usd per share) $ (0.68) $ (0.80)
Net loss per share, diluted (usd per share) $ (0.68) $ (0.80)
Weighted average number of shares outstanding, basic (in shares) 149,404,188 136,524,528
Weighted average number of shares outstanding, diluted (in shares) 149,404,188 136,524,528
[1] Includes related-party collaboration revenue from customers of $0.1 million for the three months ended March 31, 2023.
[2] Includes expenses for cost sharing payments due to a related party of $4.2 million for the three months ended March 31, 2023.