Balance Sheet Components

12 Months Ended

Dec. 31, 2022

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Balance Sheet Components

Balance Sheet Components

Property and Equipment, Net

Property and equipment, net consists of the following (in thousands):

	As of December 31,
	2022		2021
Leasehold improvements	$	43,698	$	35,235
Manufacturing and laboratory equipment	34,419		30,114
Computers equipment and purchased software	1,605		1,337
Furniture and fixtures	1,580		1,523
Total property and equipment	81,302		68,209
Less: accumulated depreciation	(37,215)		(29,344)
Total property and equipment, net	$	44,087	$	38,865

Depreciation expense was $10.4 million, $8.6 million and $8.5 million for the years ended December 31, 2022, 2021 and 2020, respectively.

Accrued Expenses and Other Current Liabilities

Accrued expenses and other current liabilities consists of the following (in thousands):

	As of December 31,
	2022		2021
Accrued manufacturing costs	$	22,307	$	9,955
Accrued compensation	17,087		19,013
Accrued clinical costs and other research & development costs	16,297		15,887
Operating lease liability, current	7,318		5,453
Other accrued costs and current liabilities	3,682		2,857
Total accrued expenses and other current liabilities	$	66,691	$	53,165