Selected Quarterly Financial Data (Unaudited) (Tables)

12 Months Ended

Dec. 31, 2019

Quarterly Financial Information Disclosure [Abstract]

Schedule of Consolidated Quarterly Financial Information (Unaudited)

The following tables provide the selected quarterly financial data for the years ended December 31, 2019 and 2018 (in thousands, except per share amounts):

	Quarter Ended
	December 31, 2019		September 30, 2019		June 30, 2019		March 31, 2019
Collaboration revenue	$	4,672	$	13,604	$	4,197	$	4,205
Loss from operations	(57,758)		(50,155)		(62,763)		(42,508)
Net loss	(54,025)		(46,260)		(58,337)		(38,992)
Net loss per share, basic and diluted(1)	$	(0.56)	$	(0.48)	$	(0.61)	$	(0.41)

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⁽¹⁾ Basic and diluted net income per share for the quarter ended December 31, 2019 is calculated using 96,078,950 shares.

	Quarter Ended
	December 31, 2018		September 30, 2018		June 30, 2018		March 31, 2018
Collaboration revenue	$	125,676	$	1,195	$	1,648	$	641
Income (loss) from operations	74,722		(37,964)		(57,382)		(25,748)
Net income (loss)	77,533		(35,371)		(54,724)		(23,678)
Net income (loss) per share, basic(1)	$	0.82	$	(0.38)	$	(0.59)	$	(0.26)
Net income (loss) per share, diluted(1)	$	0.79	$	(0.38)	$	(0.59)	$	(0.26)

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(1) Basic and diluted net income per share for the quarter ended December 31, 2018 is calculated using 94,299,096 and 97,746,224 shares, respectively, the latter of which is computed by giving effect to all dilutive potential ordinary shares including options.