Income Taxes - Components of Deferred Tax Assets and Deferred Tax Liabilities (Details) - USD ($) $ in Thousands	Dec. 31, 2024	Dec. 31, 2023
Deferred tax assets:
Net operating loss carryforwards	$ 149,735	$ 56,938
Stock-based compensation	28,586	21,364
Lease liability	6,206	5,819
Capitalized research and development costs	268,232	98,267
Research and development credits	124,116	53,946
Other	13,351	4,216
Gross deferred tax assets	590,226	240,550
Valuation allowance	(572,894)	(228,001)
Total deferred tax assets, net of valuation allowance	17,332	12,549
Deferred tax liabilities:
Right-of-use asset	(5,436)	(5,426)
Acquired intangibles	(9,727)	(6,895)
Total deferred tax liabilities	(15,163)	(12,321)
Net deferred tax assets (liabilities)	$ 2,169	$ 228