6-K

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington D.C. 20549

FORM 6-K

REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO

RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934

For the month of September 2020

Commission File Number: 001-38396

BIOFRONTERA AG

(Registrant’s name / Translation of registrant’s name into English)

Hemmelrather Weg 201, D-51377 Leverkusen Germany

(Address of principal executive office)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F [X] Form:40-F [  ]

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): N/A

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): N/A

EXHIBITS

Exhibit Number	Description
99.1	Managers’ transactions announcement according to article 19 MAR

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

BIOFRONTERA AG
By:	/s/ Hermann Lübbert
Name:	Hermann Lübbert
Title:	Chief Executive Officer
By:	/s/ Thomas Schaffer
Name:	Thomas Schaffer
Title:	Chief Financial Officer

Date: September 21, 2020

EX-99.1

Exhibit 99.1

Managers’ transactions announcement according to article 19 MAR

Biofrontera AG: Managers’ transactions announcement according to article 19 MAR

Leverkusen (pta023/21.09.2020/16:00) – Announcement

1	Details of the person discharging managerial responsibilities/person closely associated
a)	Name	Prof. Dr. Hermann Lübbert
2	Reason for the notification
a)	Position/status	Member of the managing body
b)	Initial notification
3	Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name	Biofrontera AG
b)	LEI	391200D6GFSVFGFQTL13
4	Details of the transaction(s)
a)	Description of the financial instrument, type of instrument	Share
	Identification code	DE0006046113
b)	Nature of the transaction	Another
		Exercise of options from the employee stock option plan 2015 of Biofrontera AG
		Transaction linked to the exercise of share option programmes
c)	Price(s)	Volume(s)
	2.25 EUR	180,000.00 EUR
d)	Aggregated price	Aggregated volume
	2.25 EUR	180,000.00 EUR
e)	Date of the transaction	17.09.2020 UTC+2
f)	Place of the transaction	Outside a trading venue

(end)

emitter:	Biofrontera AG Hemmelrather Weg 201 51377 Leverkusen Germany
contact person:	Investor Relations
phone:	+49 (0) 214 87 63 20
e-mail:	ir@biofrontera.com
website:	www.biofrontera.com
stock exchanges:	regulated market in Dusseldorf, Frankfurt; free market in Munich, free market in Stuttgart; open market in Berlin, Tradegate
ISIN(s):	DE0006046113 (share)
other stock exchanges:	Nasdaq