144 0001392297 XXXXXXXX LIVE 0001711933 Akoya Biosciences, Inc. 001-40344 100 CAMPUS DRIVE 6TH FLOOR MARLBOROUGH MA 01752 855.896.8401 DRISCOLL JOSEPH Officer COMMON ETRADE FINANCIAL CORPORATION

3 EDISON DRIVE ALPHARETTA GA 30005

20000 160000.00 38400000 06/15/2023 NASDAQ COMMON 06/15/2023 STOCK OPTION EXERCISE ISSUER N 20000 06/15/2023 COMPENSATION N JOSEPH DRISCOLL

100 CAMPUS DRIVE, 6TH FLOOR MARLBOROUGH, MA 01752

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100 CAMPUS DRIVE, 6TH FLOOR MARLBOROUGH MA 01752

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100 CAMPUS DRIVE, 6TH FLOOR MARLBOROUGH MA 01752

STOCK OPTION EXERCISE 06/06/2023 10000 57789.14 JOSEPH DRISCOLL

100 CAMPUS DRIVE, 6TH FLOOR MARLBOROUGH MA 01752

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100 CAMPUS DRIVE, 6TH FLOOR MARLBOROUGH MA 01752

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100 CAMPUS DRIVE, 6TH FLOOR, MARLBOROUGH MA 01752

STOCK OPTION EXERCISE 05/17/2023 10000 60316.07 06/15/2023 /s/ Joseph Driscoll