Hoth Therapeutics, Inc.

1 Rockefeller Plaza, Suite 1039

New York, New York 10020

February 6, 2019

VIA EDGAR

United States Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549

Attention:  Effie Simpson
Doug Jones
Julie Griffith
Susan Block

Re: Hoth Therapeutics, Inc.
Registration Statement on Form S-1, as amended
File No. 333-227772

Ladies and Gentlemen: 

Pursuant to Rule 461 of the General Rules and Regulations under the Securities Act of 1933, as amended (the “Act”), Hoth Therapeutics, Inc. (the “Company”) respectfully requests that the effective date of the registration statement referred to above be accelerated so that it will become effective at 5:00 p.m., Eastern Standard Time, on Monday February 11, 2019, or as soon thereafter as possible.

Please notify Richard Friedman of Sheppard, Mullin, Richter & Hampton LLP, counsel to the Company, at (212) 634-3031 as soon as possible as to the time the Registration Statement has been declared effective pursuant to this acceleration request. 

Thank you,
HOTH THERAPEUTICS, INC.
By:	/s/ Robb Knie
Name: Robb Knie
Title: Chief Executive Officer