Stockholders' Equity (Details) - USD ($)				1 Months Ended						12 Months Ended
	Sep. 30, 2021	Jan. 31, 2020	May 15, 2019	Jul. 31, 2021	Mar. 31, 2021	Dec. 31, 2020	Dec. 30, 2020	Jul. 31, 2020	Jun. 30, 2017	Dec. 31, 2021	Dec. 31, 2020	Jun. 10, 2021	Feb. 28, 2019	Nov. 30, 2016
Stockholders' Equity (Details) [Line Items]
Number of common stock sold				1,818,182	713,192						178,600
Price per share (in Dollars per share)						$ 5.45					$ 5.45
Aggregate net proceeds (in Dollars)				$ 36,900,000							$ 800,000
Gross proceeds (in Dollars)				$ 38,000,000
Shares issued						3,457,000				4,097,000	3,457,000	192,533
Purchase price, per share (in Dollars per share)					$ 21.73
Exercise of the underwriters shares								2,500,000
Proceeds from the underwritten public offering (in Dollars)								$ 23,100,000
Underwriting discounts (in Dollars)								$ 1,900,000
Common stock from a shareholder in exchange of cash (in Dollars)		$ 1,012,000
Outstanding common stock percentage		10.00%
Warrants exercised								25,000
Expected life	6 years 3 months							5 years
Exercise price, per share (in Dollars per share)								$ 10
Fair value of warrants (in Dollars)								$ 356,874
Expected dividend, percentage								0.00%
Expected volatility rate	106.00%							111.67%
Risk free rate								0.30%
Common stock issued								20,000		3,758
Cancelled the warrants								50,000
Purchase of shares										823,000
Aggregated fair value of stock options (in Dollars)										$ 14,027,000
Discount rate	0.46%
Expected dividends (in Dollars)	$ 0									0
Cash proceeds (in Dollars)										1,135,000
Stock-based compensation expense (in Dollars)						$ 2,755,000				$ 4,796,000
Unrecognized compensation cost (in Dollars)						$ 13,308,000					$ 13,308,000
Weighted-average period										2 years 6 months 7 days
Intrinsic value of warrants (in Dollars)										$ 0
Warrants exercised										6,147
Shareholder rights agreement, description							the Company one one-thousandth of a share of a newly designated series of preferred stock, Series A Junior Participating Preferred Stock, par value $0.001 per share, of the Company, at an exercise price of $300.00 per one one-thousandth of a Series A Junior Participating Preferred Share, subject to adjustment. Subject to various exceptions, the Rights become exercisable in the event any person (excluding certain exempted or grandfathered persons) becomes the beneficial owner of twenty percent or more of the Company’s common stock without the approval of the Board.
Preferred stock with par value (in Dollars per share)						$ 0.001
Undesignated preferred stock						9,955,000
Lincoln Park [Member]
Stockholders' Equity (Details) [Line Items]
Description of sale of stock			Under the terms and subject to the conditions of the securities purchase agreement, the Company had the right to sell to Lincoln Park, and Lincoln Park was obligated to purchase, up to $20.0 million in shares of the Company’s common stock, subject to certain limitations, over the 24-month period that commenced on May 15, 2019. During the year ended December 31, 2020, the Company issued 196,000 shares of its common stock to Lincoln Park for approximately $1.0 million of cash.
Employees and directors [Member]
Stockholders' Equity (Details) [Line Items]
Purchase of shares	40,000
Aggregated fair value of stock options (in Dollars)	$ 339,731
2020 ATM Program [Member]
Stockholders' Equity (Details) [Line Items]
Number of common stock sold										1,439,480
Price per share (in Dollars per share)										$ 20.17
BTIG's Commission [Member]
Stockholders' Equity (Details) [Line Items]
Aggregate net proceeds (in Dollars)										$ 14,900,000
2021 ATM Program [Member]
Stockholders' Equity (Details) [Line Items]
Number of common stock sold										713,192
Price per share (in Dollars per share)										$ 21.73
Underwritten Public Offering [Member]
Stockholders' Equity (Details) [Line Items]
Shares issued								2,500,000
Purchase price, per share (in Dollars per share)								$ 10
Option [Member]
Stockholders' Equity (Details) [Line Items]
Shares issued								326,086
Purchase price, per share (in Dollars per share)								$ 10
Warrant [Member]
Stockholders' Equity (Details) [Line Items]
Number of common stock sold									31,667
Shares issued						1,955,922				93,866	1,955,922
Warrants exercised								25,000		11,875
Exercise price, per share (in Dollars per share)								$ 5.5
Expected volatility rate										103.00%
Aggregated fair value of stock options (in Dollars)										$ 600,000
Discount rate										1.45%
Expected dividends (in Dollars)										$ 0
Warrants issued										45,386
Exercise price (in Dollars per share)									$ 1.5	$ 14.05			$ 9.6
Warrants are outstanding										28,688
Warrants intrinsic value (in Dollars)										$ 17,000
Expiration date									Jun. 30, 2022
Cash proceeds (in Dollars)										$ 18,000
Warrants are outstanding										19,792
Series A Junior Participating Preferred Stock [Member]
Stockholders' Equity (Details) [Line Items]
Designated preferred stock						45,000
Preferred stock with par value (in Dollars per share)						$ 0.001
Minimum [Member]
Stockholders' Equity (Details) [Line Items]
Expected life										6 years
Expected volatility rate										105.00%
Discount rate										0.78%
Maximum [Member]
Stockholders' Equity (Details) [Line Items]
Expected life										10 years
Expected volatility rate										114.00%
Discount rate										49.00%
2019 Incentive Stock Plan [Member]
Stockholders' Equity (Details) [Line Items]
Common stock issued								20,000
Market value of the common stock (in Dollars)								$ 230,000
Common Stock [Member]
Stockholders' Equity (Details) [Line Items]
Shares issued		220,000				33,335					33,335			33,335
Common Stock [Member] | BTIG's Commission [Member]
Stockholders' Equity (Details) [Line Items]
Aggregate net proceeds (in Dollars)										$ 28,400,000
Common Stock [Member] | Warrant [Member]
Stockholders' Equity (Details) [Line Items]
Warrants exercised								50,000
Expected life								5 years
Warrants intrinsic value (in Dollars)										$ 172,000