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                             March 28, 2023

       David Moss
       Chief Financial Officer
       Inmune Bio, Inc.
       225 NE Mizner Blvd, Suite 640
       Boca Raton, FL 33432

                                                        Re: Inmune Bio, Inc.
                                                            Form 10-K for the
fiscal year ended December 31, 2022
                                                            Filed March 2, 2023
                                                            File No. 001-38793

       Dear David Moss:

               We have limited our review of your filing to the financial
statements and related
       disclosures and have the following comment. In our comment, we may ask
you to provide us
       with information so we may better understand your disclosure.

              Please respond to the comment within ten business days by
providing the requested
       information or advise us as soon as possible when you will respond. If
you do not believe our
       comment applies to your facts and circumstances, please tell us why in
your response.

                                                        After reviewing your
response to the comment, we may have additional comments.

       Form 10-K for the fiscal year ended December 31, 2022

       Management's Discussion and Analysis of Financial Condition and Results
of Operations
       Results of Operations
       Research and Development, page 68

   1.                                                   You disclose on page 64
that you track outsourced development costs by product
                                                        candidate or
development program, but you do not allocate personnel costs, other internal
                                                        costs or external
consultant costs to specific product candidates or development programs.
                                                        Please revise your
future filings to address the following regarding your research and
                                                        development expense:
                                                            Revise to
separately quantify the research and development costs tracked during each
                                                            period presented
for each of your key research and development projects.
                                                            For all other
research and development expenses, provide other quantitative or
                                                            qualitative
disclosure that provides more transparency as to the type of research and
                                                            development
expenses incurred (i.e. quantify by nature or type of expense).
 David Moss
Inmune Bio, Inc.
March 28, 2023
Page 2
                Separately quantify the amount of tax credits that are recorded
during the period as a
              reduction to research and development expense.
                The total of costs broken out should reconcile to total
research and development
              expense on the Statements of Operations.

       In closing, we remind you that the company and its management are
responsible for the
accuracy and adequacy of their disclosures, notwithstanding any review,
comments, action or
absence of action by the staff.

       You may contact Vanessa Robertson at 202-551-3649 or Kevin Vaughn at
202-551-3494
with any questions.



FirstName LastNameDavid Moss                                   Sincerely,
Comapany NameInmune Bio, Inc.
                                                               Division of
Corporation Finance
March 28, 2023 Page 2                                          Office of Life
Sciences
FirstName LastName