X0202 SCHEDULE 13G/A 0001711463 XXXXXXXX LIVE 1 Common Stock, par value $0.0001 per share 03/31/2026 0001863127 Tyra Biosciences, Inc. 90240B106 2656 State Street Carlsbad CA 92008 Rule 13d-1(d) Todd Harris X1 2913342 0 2913342 0 2913342 N 4.8 IN Tyra Biosciences, Inc. 2656 State Street, Carlsbad, CA 92008 This statement is filed on behalf of Todd Harris (the "Reporting Person"). The principal business address of the Reporting Person is c/o Tyra Biosciences, Inc., 2656 State Street, Carlsbad, CA 92008. The Reporting Person is a citizen of the United States. Y The ownership information presented herein represents beneficial ownership of Common Stock of the Issuer as of March 31, 2026, based upon 59,469,687 shares of Common Stock outstanding as of March 31, 2026, as provided by the Issuer. The Reporting Person is the beneficial owner of 2,913,342 shares of Common Stock, which consist of (i) 1,358,631 shares of Common Stock held directly by the Reporting Person and (ii) 1,554,711 shares of Common Stock underlying stock options held directly by the Reporting Person that are currently exercisable or may be exercised within 60 days of March 31, 2026. 4.8% 2,913,342 0 2,913,342 0 N Y Y Y Y Y Y Todd Harris /s/ Todd Harris 05/14/2026