144 0001298711 XXXXXXXX LIVE 0001711279 KRYSTAL BIOTECH INC 001-38210 2100 Wharton Street Suite 701 Pittsburgh PA 15203 (412) 586-5830 SUMA KRISHNAN Officer 10% Stockholder Common Morgan Stanley Smith Barney LLC Executive Financial Services

1 New York Plaza 38th Floor New York NY 10004

25000 2903912.50 25799738 05/31/2023 NASD Common 03/31/2017 Founder Stock Issuer N 25000 03/31/2017 Cash N Suma Krishnan

2100 Wharton Street Suite 701 Pittsburgh PA 15203

Common 04/17/2023 25000 2190200.00 Krish Krishnan

2100 Wharton Street Suite 701 Pittsburgh PA 15203

Common 04/17/2023 25000 2190200.00 05/31/2023 /s/ SUMA KRISHNAN