<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2017-07-20</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001668673</issuerCik>
        <issuerName>PetIQ, Inc.</issuerName>
        <issuerTradingSymbol>PETQ</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001710694</rptOwnerCik>
            <rptOwnerName>Kennedy Ronald</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>500 E. SHORE DR., SUITE 120</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>EAGLE</rptOwnerCity>
            <rptOwnerState>ID</rptOwnerState>
            <rptOwnerZipCode>83616</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Class B Common Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.00</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F1"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Class A Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>2421465</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnotes</value>
                    <footnoteId id="F2"/>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The shares of Class B Common Stock are convertible for shares of the Issuer's Class A Common Stock as described under the heading &quot;The Transactions - Exchange Rights&quot; in the Issuer's registration statement on Form S-1 (File No. 333-218955) and have no expiration date.</footnote>
        <footnote id="F2">Includes 2,259,760 shares of Class B Common Stock held by True Science Founders, LLC (&quot;Founders&quot;).  As manager of Founders, Mr. Kennedy has voting and investment control over and may be considered the beneficial owner of all stock owned by Founders.  Mr. Kennedy disclaims beneficial ownership of such securities, and this report shall not be deemed an admission that Mr. Kennedy is the beneficial owner of the securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein, including the 297,081 shares of Class B Common Stock that represent Mr. Kennedy's interest in the Class B Common Stock owned by Founders.</footnote>
        <footnote id="F3">Includes 161,705 shares of Class B Common Stock held by Kennedy Family Investments, LLC, the manager of which is Mr. Kennedy.</footnote>
    </footnotes>

    <remarks>See Exhibit 24.1 - Power of Attorney.</remarks>

    <ownerSignature>
        <signatureName>/s/ Robert Mooney, by power of attorney</signatureName>
        <signatureDate>2017-07-20</signatureDate>
    </ownerSignature>
</ownershipDocument>
