<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/nport" xmlns:com="http://www.sec.gov/edgar/common" xmlns:ncom="http://www.sec.gov/edgar/nportcommon" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <headerData>
    <submissionType>NPORT-P</submissionType>
    <isConfidential>false</isConfidential>
    <filerInfo>

      <filer>
        <issuerCredentials>
          <cik>0001710607</cik>
          <ccc>XXXXXXXX</ccc>
        </issuerCredentials>
      </filer>


      <seriesClassInfo>
        <seriesId>S000068306</seriesId>
        <classId>C000218645</classId>
      </seriesClassInfo>


    </filerInfo>
  </headerData>
  <formData>
    <genInfo>
      <regName>American Century ETF Trust</regName>
      <regFileNumber>811-23305</regFileNumber>
      <regCik>0001710607</regCik>
      <regLei>5493006IKK34YJD98183</regLei>
      <regStreet1>4500 Main St</regStreet1>
      <regCity>Kansas City</regCity>
      <regStateConditional regCountry="US" regState="US-MO"/>
      <regZipOrPostalCode>64111</regZipOrPostalCode>
      <regPhone>816-531-5575</regPhone>
      <seriesName>American Century Mid Cap Growth Impact ETF</seriesName>
      <seriesId>S000068306</seriesId>
      <seriesLei>549300RZJCDU6SCEXC76</seriesLei>
      <repPdEnd>2026-08-31</repPdEnd>
      <repPdDate>2026-08-31</repPdDate>
      <isFinalFiling>N</isFinalFiling>
    </genInfo>
    <fundInfo>
      <totAssets>104818628.160000000000</totAssets>
      <totLiabs>39522.740000000000</totLiabs>
      <netAssets>104779105.420000000000</netAssets>
      <assetsAttrMiscSec>0.000000000000</assetsAttrMiscSec>
      <assetsInvested>0.000000000000</assetsInvested>
      <amtPayOneYrBanksBorr>0.000000000000</amtPayOneYrBanksBorr>
      <amtPayOneYrCtrldComp>0.000000000000</amtPayOneYrCtrldComp>
      <amtPayOneYrOthAffil>0.000000000000</amtPayOneYrOthAffil>
      <amtPayOneYrOther>0.000000000000</amtPayOneYrOther>
      <amtPayAftOneYrBanksBorr>0.000000000000</amtPayAftOneYrBanksBorr>
      <amtPayAftOneYrCtrldComp>0.000000000000</amtPayAftOneYrCtrldComp>
      <amtPayAftOneYrOthAffil>0.000000000000</amtPayAftOneYrOthAffil>
      <amtPayAftOneYrOther>0.000000000000</amtPayAftOneYrOther>
      <delayDeliv>0.000000000000</delayDeliv>
      <standByCommit>0.000000000000</standByCommit>
      <liquidPref>0.000000000000</liquidPref>
      <cshNotRptdInCorD>0.000000000000</cshNotRptdInCorD>
      <isNonCashCollateral>N</isNonCashCollateral>
      <returnInfo>
        <monthlyTotReturns>
          <monthlyTotReturn classId="C000218645" rtn1="1.285434036116" rtn2="-2.933898236084" rtn3="4.631153864013"/>
        </monthlyTotReturns>
        <othMon1 netRealizedGain="-667098.9700" netUnrealizedAppr="1970116.4200"/>
        <othMon2 netRealizedGain="166274.7600" netUnrealizedAppr="-3178856.7800"/>
        <othMon3 netRealizedGain="-430308.8700" netUnrealizedAppr="5056634.1000"/>
      </returnInfo>
      <mon1Flow redemption="1685862.5000" reinvestment="0.0000" sales="2000594.0000"/>
      <mon2Flow redemption="345718.0000" reinvestment="0.0000" sales="1736072.5000"/>
      <mon3Flow redemption="0.0000" reinvestment="0.0000" sales="698873.0000"/>



    </fundInfo>
    <invstOrSecs>
      <invstOrSec>
        <name>Affirm Holdings Inc</name>
        <lei>N/A</lei>
        <title>Affirm Holdings Inc</title>
        <cusip>00827B106</cusip>
        <identifiers>
          <isin value="US00827B1061"/>
          <ticker value="AFRM"/>
          <other otherDesc="SEDOL" value="BMF9NM8"/>
        </identifiers>
        <balance>13873.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1032844.8500000000</valUSD>
        <pctVal>0.9857355108</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Alnylam Pharmaceuticals Inc</name>
        <lei>529900S3ZI14OWRJII50</lei>
        <title>Alnylam Pharmaceuticals Inc</title>
        <cusip>02043Q107</cusip>
        <identifiers>
          <isin value="US02043Q1076"/>
          <ticker value="ALNY"/>
          <other otherDesc="SEDOL" value="B00FWN1"/>
        </identifiers>
        <balance>6371.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1533435.9900000000</valUSD>
        <pctVal>1.4634940658</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Cencora Inc</name>
        <lei>AI8GXW8LG5WK7E9UD086</lei>
        <title>Cencora Inc</title>
        <cusip>03073E105</cusip>
        <identifiers>
          <isin value="US03073E1055"/>
          <ticker value="COR"/>
          <other otherDesc="SEDOL" value="2795393"/>
        </identifiers>
        <balance>5428.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1756500.8000000000</valUSD>
        <pctVal>1.6763846121</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Axon Enterprise Inc</name>
        <lei>549300QP2IEEGFE16681</lei>
        <title>Axon Enterprise Inc</title>
        <cusip>05464C101</cusip>
        <identifiers>
          <isin value="US05464C1018"/>
          <ticker value="AXON"/>
          <other otherDesc="SEDOL" value="BDT5S35"/>
        </identifiers>
        <balance>2411.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1365976.1600000000</valUSD>
        <pctVal>1.3036722871</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Cadence Design Systems Inc</name>
        <lei>GCT7RXJOGLXPV0NXZY22</lei>
        <title>Cadence Design Systems Inc</title>
        <cusip>127387108</cusip>
        <identifiers>
          <isin value="US1273871087"/>
          <ticker value="CDNS"/>
          <other otherDesc="SEDOL" value="2302232"/>
        </identifiers>
        <balance>13058.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4423789.2400000000</valUSD>
        <pctVal>4.2220147063</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Cameco Corp</name>
        <lei>N4BHALMXL3GMZKCUON55</lei>
        <title>Cameco Corp</title>
        <cusip>13321L108</cusip>
        <identifiers>
          <isin value="CA13321L1085"/>
          <ticker value="CCJ"/>
          <other otherDesc="SEDOL" value="2158684"/>
        </identifiers>
        <balance>29307.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2894359.3200000000</valUSD>
        <pctVal>2.7623439887</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CA</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Capstone Copper Corp</name>
        <lei>549300III6KGKKC42W63</lei>
        <title>Capstone Copper Corp</title>
        <cusip>14071L108</cusip>
        <identifiers>
          <isin value="CA14071L1085"/>
          <ticker value="CS"/>
          <other otherDesc="SEDOL" value="BMY5XY9"/>
        </identifiers>
        <balance>267044.0000000000</balance>
        <units>NS</units>
        <currencyConditional curCd="CAD" exchangeRt="1.3859500000"/>
        <valUSD>3098284.5800000000</valUSD>
        <pctVal>2.9569679638</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CA</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Chipotle Mexican Grill Inc</name>
        <lei>529900REP5VGTPCP1J71</lei>
        <title>Chipotle Mexican Grill Inc</title>
        <cusip>169656105</cusip>
        <identifiers>
          <isin value="US1696561059"/>
          <ticker value="CMG"/>
          <other otherDesc="SEDOL" value="B0X7DZ3"/>
        </identifiers>
        <balance>138808.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5278868.2400000000</valUSD>
        <pctVal>5.0380924888</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Cloudflare Inc</name>
        <lei>5493007DY18BGNLDWU14</lei>
        <title>Cloudflare Inc</title>
        <cusip>18915M107</cusip>
        <identifiers>
          <isin value="US18915M1071"/>
          <ticker value="NET"/>
          <other otherDesc="SEDOL" value="BJXC5M2"/>
        </identifiers>
        <balance>32795.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>10006082.4500000000</valUSD>
        <pctVal>9.5496925746</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Corpay Inc</name>
        <lei>549300DG6RR0NQSFLN74</lei>
        <title>Corpay Inc</title>
        <cusip>219948106</cusip>
        <identifiers>
          <isin value="US2199481068"/>
          <ticker value="CPAY"/>
          <other otherDesc="SEDOL" value="BMX5GK7"/>
        </identifiers>
        <balance>3863.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1561810.9000000000</valUSD>
        <pctVal>1.4905747608</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Coupang Inc</name>
        <lei>549300XR4L1D80AK4W76</lei>
        <title>Coupang Inc</title>
        <cusip>22266T109</cusip>
        <identifiers>
          <isin value="US22266T1097"/>
          <ticker value="CPNG"/>
          <other otherDesc="SEDOL" value="BNYHDF3"/>
        </identifiers>
        <balance>183709.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2950366.5400000000</valUSD>
        <pctVal>2.8157966497</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Dexcom Inc</name>
        <lei>549300YSK3QDSFR5EU59</lei>
        <title>Dexcom Inc</title>
        <cusip>252131107</cusip>
        <identifiers>
          <isin value="US2521311074"/>
          <ticker value="DXCM"/>
          <other otherDesc="SEDOL" value="B0796X4"/>
        </identifiers>
        <balance>17334.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1578434.0400000000</valUSD>
        <pctVal>1.5064396987</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Duolingo Inc</name>
        <lei>N/A</lei>
        <title>Duolingo Inc</title>
        <cusip>26603R106</cusip>
        <identifiers>
          <isin value="US26603R1068"/>
          <ticker value="DUOL"/>
          <other otherDesc="SEDOL" value="BMCM6P4"/>
        </identifiers>
        <balance>12664.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1878831.0400000000</valUSD>
        <pctVal>1.7931352176</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Hilton Worldwide Holdings Inc</name>
        <lei>549300HVGPK36ICB0B89</lei>
        <title>Hilton Worldwide Holdings Inc</title>
        <cusip>43300A203</cusip>
        <identifiers>
          <isin value="US43300A2033"/>
          <ticker value="HLT"/>
          <other otherDesc="SEDOL" value="BYVMW06"/>
        </identifiers>
        <balance>13886.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4391864.0800000000</valUSD>
        <pctVal>4.1915456926</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>State Street Institutional US Government Money Market Fund</name>
        <lei>549300BZ5TGIFZUZDZ37</lei>
        <title>State Street Institutional US Government Money Market Fund</title>
        <cusip>857492706</cusip>
        <identifiers>
          <isin value="US8574927062"/>
          <ticker value="GVMXX"/>
          <other otherDesc="SEDOL" value="B284MN4"/>
        </identifiers>
        <balance>1182386.4300000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1182386.4300000000</valUSD>
        <pctVal>1.1284563132</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Hubbell Inc</name>
        <lei>54930088VDQ6840Y6597</lei>
        <title>Hubbell Inc</title>
        <cusip>443510607</cusip>
        <identifiers>
          <isin value="US4435106079"/>
          <ticker value="HUBB"/>
          <other otherDesc="SEDOL" value="BDFG6S3"/>
        </identifiers>
        <balance>8246.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3735438.0000000000</valUSD>
        <pctVal>3.5650600232</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IDEXX Laboratories Inc</name>
        <lei>OGMTXK0LUU1HKV2P0J84</lei>
        <title>IDEXX Laboratories Inc</title>
        <cusip>45168D104</cusip>
        <identifiers>
          <isin value="US45168D1046"/>
          <ticker value="IDXX"/>
          <other otherDesc="SEDOL" value="2459202"/>
        </identifiers>
        <balance>2505.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1394508.4500000000</valUSD>
        <pctVal>1.3309031838</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MACOM Technology Solutions Holdings Inc</name>
        <lei>N/A</lei>
        <title>MACOM Technology Solutions Holdings Inc</title>
        <cusip>55405Y100</cusip>
        <identifiers>
          <isin value="US55405Y1001"/>
          <ticker value="MTSI"/>
          <other otherDesc="SEDOL" value="B5B15Y5"/>
        </identifiers>
        <balance>12946.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3415543.1800000000</valUSD>
        <pctVal>3.2597560041</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Monolithic Power Systems Inc</name>
        <lei>529900TB7O85LSZ1XU31</lei>
        <title>Monolithic Power Systems Inc</title>
        <cusip>609839105</cusip>
        <identifiers>
          <isin value="US6098391054"/>
          <ticker value="MPWR"/>
          <other otherDesc="SEDOL" value="B01Z7J1"/>
        </identifiers>
        <balance>4065.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5153485.0500000000</valUSD>
        <pctVal>4.9184281822</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Natera Inc</name>
        <lei>529900CQ3OZ0A0VYVU59</lei>
        <title>Natera Inc</title>
        <cusip>632307104</cusip>
        <identifiers>
          <isin value="US6323071042"/>
          <ticker value="NTRA"/>
          <other otherDesc="SEDOL" value="BYQRG48"/>
        </identifiers>
        <balance>3238.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1042506.4800000000</valUSD>
        <pctVal>0.9949564618</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Okta Inc</name>
        <lei>549300N8J06I8MRHU620</lei>
        <title>Okta Inc</title>
        <cusip>679295105</cusip>
        <identifiers>
          <isin value="US6792951054"/>
          <ticker value="OKTA"/>
          <other otherDesc="SEDOL" value="BDFZSP1"/>
        </identifiers>
        <balance>50761.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8783683.4400000000</valUSD>
        <pctVal>8.3830487050</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Insmed Inc</name>
        <lei>529900Q55QAG41CCAC11</lei>
        <title>Insmed Inc</title>
        <cusip>457669307</cusip>
        <identifiers>
          <isin value="US4576693075"/>
          <ticker value="INSM"/>
          <other otherDesc="SEDOL" value="2614487"/>
        </identifiers>
        <balance>10715.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1305301.3000000000</valUSD>
        <pctVal>1.2457648830</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Reddit Inc</name>
        <lei>529900APN1YHPBHPI679</lei>
        <title>Reddit Inc</title>
        <cusip>75734B100</cusip>
        <identifiers>
          <isin value="US75734B1008"/>
          <ticker value="RDDT"/>
          <other otherDesc="SEDOL" value="BMVNLY2"/>
        </identifiers>
        <balance>15594.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2304949.1400000000</valUSD>
        <pctVal>2.1998175407</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Republic Services Inc</name>
        <lei>NKNQHM6BLECKVOQP7O46</lei>
        <title>Republic Services Inc</title>
        <cusip>760759100</cusip>
        <identifiers>
          <isin value="US7607591002"/>
          <ticker value="RSG"/>
          <other otherDesc="SEDOL" value="2262530"/>
        </identifiers>
        <balance>12094.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2671806.4800000000</valUSD>
        <pctVal>2.5499420608</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Revolution Medicines Inc</name>
        <lei>549300JU3X0LBCQ65892</lei>
        <title>Revolution Medicines Inc</title>
        <cusip>76155X100</cusip>
        <identifiers>
          <isin value="US76155X1000"/>
          <ticker value="RVMD"/>
          <other otherDesc="SEDOL" value="BL71K91"/>
        </identifiers>
        <balance>8044.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1653605.0800000000</valUSD>
        <pctVal>1.5781820940</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Structure Therapeutics Inc</name>
        <lei>N/A</lei>
        <title>Structure Therapeutics Inc</title>
        <cusip>86366E106</cusip>
        <identifiers>
          <isin value="US86366E1064"/>
          <ticker value="GPCR"/>
          <other otherDesc="SEDOL" value="BQS9486"/>
        </identifiers>
        <balance>13657.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>626992.8700000000</valUSD>
        <pctVal>0.5983949448</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Targa Resources Corp</name>
        <lei>5493003QENHHS261UR94</lei>
        <title>Targa Resources Corp</title>
        <cusip>87612G101</cusip>
        <identifiers>
          <isin value="US87612G1013"/>
          <ticker value="TRGP"/>
          <other otherDesc="SEDOL" value="B55PZY3"/>
        </identifiers>
        <balance>17957.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5273073.0500000000</valUSD>
        <pctVal>5.0325616246</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Toast Inc</name>
        <lei>N/A</lei>
        <title>Toast Inc</title>
        <cusip>888787108</cusip>
        <identifiers>
          <isin value="US8887871080"/>
          <ticker value="TOST"/>
          <other otherDesc="SEDOL" value="BP6D7B7"/>
        </identifiers>
        <balance>54445.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1856030.0500000000</valUSD>
        <pctVal>1.7713742092</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Vertiv Holdings Co</name>
        <lei>549300KTTIRAOGXCRV69</lei>
        <title>Vertiv Holdings Co</title>
        <cusip>92537N108</cusip>
        <identifiers>
          <isin value="US92537N1081"/>
          <ticker value="VRT"/>
          <other otherDesc="SEDOL" value="BL3LWS8"/>
        </identifiers>
        <balance>9288.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2402991.3600000000</valUSD>
        <pctVal>2.2933879330</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Viking Therapeutics Inc</name>
        <lei>529900IVC72YPFA25M37</lei>
        <title>Viking Therapeutics Inc</title>
        <cusip>92686J106</cusip>
        <identifiers>
          <isin value="US92686J1060"/>
          <ticker value="VKTX"/>
          <other otherDesc="SEDOL" value="BQQG1V1"/>
        </identifiers>
        <balance>21939.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>719160.4200000000</valUSD>
        <pctVal>0.6863586181</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Vistra Corp</name>
        <lei>549300KP43CPCUJOOG15</lei>
        <title>Vistra Corp</title>
        <cusip>92840M102</cusip>
        <identifiers>
          <isin value="US92840M1027"/>
          <ticker value="VST"/>
          <other otherDesc="SEDOL" value="BZ8VJQ8"/>
        </identifiers>
        <balance>20614.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2831745.1800000000</valUSD>
        <pctVal>2.7025857576</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>WESCO International Inc</name>
        <lei>529900TXOGREY3WNJ434</lei>
        <title>WESCO International Inc</title>
        <cusip>95082P105</cusip>
        <identifiers>
          <isin value="US95082P1057"/>
          <ticker value="WCC"/>
          <other otherDesc="SEDOL" value="2416973"/>
        </identifiers>
        <balance>13158.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4478983.2000000000</valUSD>
        <pctVal>4.2746912011</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>West Pharmaceutical Services Inc</name>
        <lei>5493007NKRGM1RJQ1P16</lei>
        <title>West Pharmaceutical Services Inc</title>
        <cusip>955306105</cusip>
        <identifiers>
          <isin value="US9553061055"/>
          <ticker value="WST"/>
          <other otherDesc="SEDOL" value="2950482"/>
        </identifiers>
        <balance>2093.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>713943.2300000000</valUSD>
        <pctVal>0.6813793906</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Zoetis Inc</name>
        <lei>549300HD9Q1LOC9KLJ48</lei>
        <title>Zoetis Inc</title>
        <cusip>98978V103</cusip>
        <identifiers>
          <isin value="US98978V1035"/>
          <ticker value="ZTS"/>
          <other otherDesc="SEDOL" value="B95WG16"/>
        </identifiers>
        <balance>6253.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>482106.3000000000</valUSD>
        <pctVal>0.4601168316</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Johnson Controls International plc</name>
        <lei>549300XQ6S1GYKGBL205</lei>
        <title>Johnson Controls International plc</title>
        <cusip>G51502105</cusip>
        <identifiers>
          <isin value="IE00BY7QL619"/>
          <ticker value="JCI"/>
          <other otherDesc="SEDOL" value="BY7QL61"/>
        </identifiers>
        <balance>34664.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4791951.3600000000</valUSD>
        <pctVal>4.5733844938</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NU Holdings Ltd/Cayman Islands</name>
        <lei>5493002DG1RHWK9W2X27</lei>
        <title>NU Holdings Ltd/Cayman Islands</title>
        <cusip>G6683N103</cusip>
        <identifiers>
          <isin value="KYG6683N1034"/>
          <ticker value="NU"/>
          <other otherDesc="SEDOL" value="BN6NP19"/>
        </identifiers>
        <balance>123476.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1796575.8000000000</valUSD>
        <pctVal>1.7146317415</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>BR</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>On Holding AG</name>
        <lei>506700FB3467B9W95526</lei>
        <title>On Holding AG</title>
        <cusip>H5919C104</cusip>
        <identifiers>
          <isin value="CH1134540470"/>
          <ticker value="ONON"/>
          <other otherDesc="SEDOL" value="BPF0FP9"/>
        </identifiers>
        <balance>7640.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>217740.0000000000</valUSD>
        <pctVal>0.2078086076</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CH</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Spotify Technology SA</name>
        <lei>549300B4X0JHWV0DTD60</lei>
        <title>Spotify Technology SA</title>
        <cusip>L8681T102</cusip>
        <identifiers>
          <isin value="LU1778762911"/>
          <ticker value="SPOT"/>
          <other otherDesc="SEDOL" value="BFZ1K46"/>
        </identifiers>
        <balance>4075.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2215251.5000000000</valUSD>
        <pctVal>2.1142111217</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>SE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <signature>
      <ncom:dateSigned>2026-10-29</ncom:dateSigned>
      <ncom:nameOfApplicant>American Century ETF Trust</ncom:nameOfApplicant>
      <ncom:signature>Amy R. Bitter</ncom:signature>
      <ncom:signerName>Amy R. Bitter</ncom:signerName>
      <ncom:title>Assistant Treasurer</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
