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      <seriesName>American Century Mid Cap Growth Impact ETF</seriesName>
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      <invstOrSec>
        <name>Palo Alto Networks Inc</name>
        <lei>549300QXR2YVZV231H43</lei>
        <title>Palo Alto Networks Inc</title>
        <cusip>697435105</cusip>
        <identifiers>
          <isin value="US6974351057"/>
          <ticker value="PANW"/>
          <other otherDesc="SEDOL" value="B87ZMX0"/>
        </identifiers>
        <balance>2786.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1523774.8400000000</valUSD>
        <pctVal>6.1798059352</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Peloton Interactive Inc</name>
        <lei>N/A</lei>
        <title>Peloton Interactive Inc</title>
        <cusip>70614W100</cusip>
        <identifiers>
          <isin value="US70614W1009"/>
          <ticker value="PTON"/>
          <other otherDesc="SEDOL" value="BJ7WJS2"/>
        </identifiers>
        <balance>6953.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>305932.0000000000</valUSD>
        <pctVal>1.2407347462</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Plug Power Inc</name>
        <lei>549300JPDKRSJ8JSM954</lei>
        <title>Plug Power Inc</title>
        <cusip>72919P202</cusip>
        <identifiers>
          <isin value="US72919P2020"/>
          <ticker value="PLUG"/>
          <other otherDesc="SEDOL" value="2508386"/>
        </identifiers>
        <balance>5777.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>230213.4500000000</valUSD>
        <pctVal>0.9336513554</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>State Street Institutional US Government Money Market Fund</name>
        <lei>549300BZ5TGIFZUZDZ37</lei>
        <title>State Street Institutional US Government Money Market Fund</title>
        <cusip>857492706</cusip>
        <identifiers>
          <isin value="US8574927062"/>
          <ticker value="GVMXX"/>
          <other otherDesc="SEDOL" value="B284MN4"/>
        </identifiers>
        <balance>597870.4500000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>597870.4500000000</valUSD>
        <pctVal>2.4247173916</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Square Inc</name>
        <lei>549300OHIIUWSTIZME52</lei>
        <title>Square Inc</title>
        <cusip>852234103</cusip>
        <identifiers>
          <isin value="US8522341036"/>
          <ticker value="SQ"/>
          <other otherDesc="SEDOL" value="BYNZGK1"/>
        </identifiers>
        <balance>3205.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>667697.6500000000</valUSD>
        <pctVal>2.7079078825</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Turning Point Therapeutics Inc</name>
        <lei>N/A</lei>
        <title>Turning Point Therapeutics Inc</title>
        <cusip>90041T108</cusip>
        <identifiers>
          <isin value="US90041T1088"/>
          <ticker value="TPTX"/>
          <other otherDesc="SEDOL" value="BJXBP30"/>
        </identifiers>
        <balance>3333.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>126853.9800000000</valUSD>
        <pctVal>0.5144677271</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Twilio Inc</name>
        <lei>5493004W8TRGD63APX93</lei>
        <title>Twilio Inc</title>
        <cusip>90138F102</cusip>
        <identifiers>
          <isin value="US90138F1021"/>
          <ticker value="TWLO"/>
          <other otherDesc="SEDOL" value="BD6P5Q0"/>
        </identifiers>
        <balance>2755.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>788343.2500000000</valUSD>
        <pctVal>3.1971969660</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Veeva Systems Inc</name>
        <lei>549300YZEXPDB92M2F02</lei>
        <title>Veeva Systems Inc</title>
        <cusip>922475108</cusip>
        <identifiers>
          <isin value="US9224751084"/>
          <ticker value="VEEV"/>
          <other otherDesc="SEDOL" value="BFH3N85"/>
        </identifiers>
        <balance>3029.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>855934.8200000000</valUSD>
        <pctVal>3.4713206584</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Zurn Water Solutions Corp</name>
        <lei>549300AM3633XDFU1Q85</lei>
        <title>Zurn Water Solutions Corp</title>
        <cusip>98983L108</cusip>
        <identifiers>
          <isin value="US98983L1089"/>
          <ticker value="ZWS"/>
          <other otherDesc="SEDOL" value="BMV1ZD3"/>
        </identifiers>
        <balance>14060.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>492803.0000000000</valUSD>
        <pctVal>1.9986068967</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Horizon Therapeutics Plc</name>
        <lei>N/A</lei>
        <title>Horizon Therapeutics Plc</title>
        <cusip>G46188101</cusip>
        <identifiers>
          <isin value="IE00BQPVQZ61"/>
          <ticker value="HZNP"/>
          <other otherDesc="SEDOL" value="BQPVQZ6"/>
        </identifiers>
        <balance>4971.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>515790.9600000000</valUSD>
        <pctVal>2.0918366364</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Aptiv PLC</name>
        <lei>N/A</lei>
        <title>Aptiv PLC</title>
        <cusip>G6095L109</cusip>
        <identifiers>
          <isin value="JE00B783TY65"/>
          <ticker value="APTV"/>
          <other otherDesc="SEDOL" value="B783TY6"/>
        </identifiers>
        <balance>6843.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1097275.0500000000</valUSD>
        <pctVal>4.4500976710</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Trane Technologies PLC</name>
        <lei>N/A</lei>
        <title>Trane Technologies PLC</title>
        <cusip>G8994E103</cusip>
        <identifiers>
          <isin value="IE00BK9ZQ967"/>
          <ticker value="TT"/>
          <other otherDesc="SEDOL" value="BK9ZQ96"/>
        </identifiers>
        <balance>4931.0000000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>920371.1500000000</valUSD>
        <pctVal>3.7326479911</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <signature>
      <ncom:dateSigned>2022-01-24</ncom:dateSigned>
      <ncom:nameOfApplicant>American Century ETF Trust</ncom:nameOfApplicant>
      <ncom:signature>Amy R. Bitter</ncom:signature>
      <ncom:signerName>Amy R. Bitter</ncom:signerName>
      <ncom:title>Assistant Treasurer</ncom:title>
    </signature>
  </formData>
  <documents>XXXX</documents>
</edgarSubmission>
