X0609 4 2026-07-01 false 0001710072 Edgewise Therapeutics, Inc. EWTX 0001853529 Russell Alan J false C/O EDGEWISE THERAPEUTICS, INC. 1715 38TH STREET BOULDER CO 80301 true true false false Chief Scientific Officer true Common Stock 2026-07-01 4 M false 130352.00 0.45 A 154907.00 D Common Stock 2026-07-01 4 M false 69648.00 0.18 A 224555.00 D Common Stock 2026-07-01 4 S false 130352.00 39.406 D 94203.00 D Common Stock 2026-07-01 4 S false 69648.00 39.4089 D 24555.00 D Stock Option (Right to Buy) 0.45 2026-07-01 4 M false 130352.00 0.00 D 2028-08-30 Common Stock 130352.00 0.00 D Stock Option (Right to Buy) 0.18 2026-07-01 4 M false 69648.00 0.00 D 2032-06-27 Common Stock 69648.00 1077717.00 D Includes 107 shares purchased on November 15, 2025 and 1,048 shares purchased on May 15, 2026 pursuant to the Edgewise Therapeutics, Inc. 2021 Employee Stock Purchase Plan. The price reported in column 4 is an average price. These shares were sold in multiple transactions at prices ranging from $38.77 to $40.81, inclusive. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. The price reported in column 4 is an average price. These shares were sold in multiple transactions at prices ranging from $38.77 to $40.905, inclusive. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. 1/48th of the shares subject to the option vest each month beginning on September 10, 2018, subject to the Reporting Person continuing as a service provider through each vest date. 1/48th of the shares subject to the option vest each month beginning on July 27, 2017, subject to the Reporting Person continuing as a service provider through each vest date. /s/ John R. Moore Attorney-in-Fact for Alan J Russell 2026-07-01