X0306 4 2022-10-03 false 0001710072 Edgewise Therapeutics, Inc. EWTX 0001191702 MOORE JOHN R C/O EDGEWISE THERAPEUTICS, INC. 3145 COLORADO AVE BOULDER CO 80303 false true false false General Counsel Common Stock 2022-10-03 4 M false 4730.00 1.93 A 7730.00 D Common Stock 2022-10-03 4 S false 4730.00 9.7579 D 3000.00 D Stock Option (Right to Buy) 1.93 2022-10-03 4 M false 4730.00 0.00 D 2030-12-15 Common Stock 4730.00 122997.00 D The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 Plan adopted by the Reporting Person on March 16, 2022. The price reported in column 4 is an average price. These shares were sold in multiple transactions at prices ranging from $9.47 to $10.00, inclusive. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote. 1/48th of the shares subject to the option vest each month beginning on January 3, 2021, subject to the Reporting Person continuing as a service provider through each vest date. /s/ John R. Moore 2022-10-05