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CONDENSED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2026
Mar. 31, 2025
Cash flows from operating activities    
Net loss $ (49,013) $ (40,798)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation 537 513
Stock-based compensation 8,715 9,059
Accretion of discount on marketable securities, net (1,013) (1,923)
Amortization of right-of-use asset 53 41
Changes in assets and liabilities:    
Prepaid expenses and other assets 3,045 (1,478)
Accounts payable 1,446 2,858
Accrued compensation (6,752) (6,081)
Accrued other expenses and other liabilities 635 122
Lease liability (196) (179)
Net cash used in operating activities (42,543) (37,866)
Cash flows from investing activities    
Purchases of marketable securities (110,152) (122,180)
Sales of marketable securities 3,966 15,000
Maturities of marketable securities 108,879 151,122
Purchases of property and equipment (260) (44)
Net cash provided by investing activities 2,433 43,898
Cash flows from financing activities    
Exercise of stock options 12,173 2,261
Payment of deferred offering costs   (38)
Net cash provided by financing activities 12,173 2,223
Net change in cash and cash equivalents (27,937) 8,255
Cash and cash equivalents at beginning of period 61,148 41,666
Cash and cash equivalents at end of period 33,211 49,921
Supplemental disclosures of non-cash investing and financing activities:    
Property and equipment purchases included in accounts payable and accrued other expenses $ 41  
Deferred offering costs included in accounts payable and accrued other expenses   $ 395