Insider Trading Arrangements

3 Months Ended

Mar. 31, 2026

shares

Trading Arrangements, by Individual

Non-Rule 10b5-1 Arrangement Adopted

false

Non-Rule 10b5-1 Arrangement Terminated

false

Alan Russell

Trading Arrangements, by Individual

Material Terms of Trading Arrangement

On March 13, 2026, Alan Russell, Chief Scientific Officer and Director, adopted a Rule 10b5-1 trading arrangement providing for the sale from time to time of up to 200,000 shares of our common stock. The trading arrangement is intended to satisfy the affirmative defense in Rule 10b5-1(c). The duration of the trading arrangement is until July 1, 2027, or earlier if all transactions under the trading arrangement are completed.

Name

Alan Russell

Title

Chief Scientific Officer and Director

Rule 10b5-1 Arrangement Adopted

true

Adoption Date

March 13, 2026

Aggregate Available

200,000

Expiration Date

July 1, 2027