<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2018-08-27</periodOfReport>

    <notSubjectToSection16>1</notSubjectToSection16>

    <issuer>
        <issuerCik>0001668397</issuerCik>
        <issuerName>Medpace Holdings, Inc.</issuerName>
        <issuerTradingSymbol>MEDP</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001709863</rptOwnerCik>
            <rptOwnerName>Medpace Limited Partnership</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>EAST WING, TRAFALGAR COURT, LES BANQUES</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ST. PETER PORT</rptOwnerCity>
            <rptOwnerState>Y7</rptOwnerState>
            <rptOwnerZipCode>GY1   3PP</rptOwnerZipCode>
            <rptOwnerStateDescription>GUERNSEY</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001709888</rptOwnerCik>
            <rptOwnerName>Medpace GP Ltd</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>EAST WING, TRAFALGAR COURT, LES BANQUES</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ST. PETER PORT</rptOwnerCity>
            <rptOwnerState>Y7</rptOwnerState>
            <rptOwnerZipCode>GY1 3PP</rptOwnerZipCode>
            <rptOwnerStateDescription>GUERNSEY</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001657322</rptOwnerCik>
            <rptOwnerName>Cinven Capital Management (V) General Partner Ltd</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>EAST WING, TRAFALGAR COURT, LES BANQUES</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ST. PETER PORT</rptOwnerCity>
            <rptOwnerState>Y7</rptOwnerState>
            <rptOwnerZipCode>GY1 3PP</rptOwnerZipCode>
            <rptOwnerStateDescription>GUERNSEY</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001677850</rptOwnerCik>
            <rptOwnerName>Cinven Capital Management (V) Limited Partnership Inc</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>EAST WING, TRAFALGAR COURT, LES BANQUES</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>ST. PETER PORT</rptOwnerCity>
            <rptOwnerState>Y7</rptOwnerState>
            <rptOwnerZipCode>GY1 3PP</rptOwnerZipCode>
            <rptOwnerStateDescription>GUERNSEY</rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2018-08-27</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>5224997</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>54.75</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnotes</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The shares of Common Stock reported herein are held of record by Medpace Limited Partnership.  Cinven Capital Management (V) General Partner Limited (&quot;Cinven MGP&quot;) is the Managing General Partner of Cinven Capital Management (V) Limited Partnership Incorporated (&quot;GPLP&quot;), which is the Managing General Partner of a majority of the stockholders of Medpace GP Limited (&quot;Medpace GP&quot;), which is the general partner of Medpace Limited Partnership.  The board of directors of Medpace GP has voting and investment discretion with respect to the shares held of record by Medpace Limited Partnership.  Cinven MGP, as Managing General Partner of the Managing General Partner of a majority of the stockholders of Medpace GP, indirectly controls Medpace GP.</footnote>
        <footnote id="F2">(Continued from Footnote 1) Decisions of Cinven MGP are taken by its board of directors, which is comprised of Robin Hall, Brian Linden, Hayley Tanguy, John Boothman, Rupert Dorey and William Scott.  Each such director disclaims beneficial ownership of the shares reported herein.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>Medpace Limited Partnership, acting through its general partner, Medpace GP Limited, By: /s/ Belinda Ridout, Director</signatureName>
        <signatureDate>2018-08-27</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Medpace GP Limited, By: /s/ Belinda Ridout, Director</signatureName>
        <signatureDate>2018-08-27</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Cinven Capital Management (V) General Partner Limited By: /s/ Hayley Tanguy, Director</signatureName>
        <signatureDate>2018-08-27</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Cinven Capital Management (V) Limited Partnership Incorporated By: /s/ Hayley Tanguy, Director</signatureName>
        <signatureDate>2018-08-27</signatureDate>
    </ownerSignature>
</ownershipDocument>
