Document and Entity Information Document Information [Table] Document Information [Line Items] Document Type Document Quarterly Report Document Transition Report Document Period End Date Entity File Number Entity Registrant Name Entity Incorporation, State or Country Code Entity Tax Identification Number Entity Address, Address Line One Entity Address, Address Line Two Entity Address, City or Town Entity Address, State or Province Entity Address, Postal Zip Code City Area Code Local Phone Number Title of 12(b) Security Trading Symbol Security Exchange Name Entity Current Reporting Status Entity Interactive Data Current Entity Filer Category Entity Small Business Entity Emerging Growth Company Entity Shell Company Entity Common Stock, Shares Outstanding Current Fiscal Year End Date Document Fiscal Year Focus Document Fiscal Period Focus Entity Central Index Key Amendment Flag CONDENSED CONSOLIDATED BALANCE SHEETS Statement [Table] Statement [Line Items] Statement Assets [Abstract] Assets Current assets: Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Short-term Investments Investments Investments Amount of asset related to consideration paid in advance and other for costs that provide economic benefits within a future period of one year or the normal operating cycle, if longer. Prepaid Expense And Other, Current Prepaid expenses and other current assets Assets, Current Total current assets Operating Lease, Right-of-Use Asset Operating lease, right-of-use-asset Property, Plant and Equipment, Net Property, plant and equipment, net Property, plant and equipment, net Restricted Cash, Noncurrent Restricted cash Restricted cash (non-current) Assets Total assets Liabilities and Equity [Abstract] Liabilities and Stockholders' Equity Liabilities, Current [Abstract] Current liabilities: Accounts Payable, Current Accounts payable Carrying value as of the balance sheet date of obligations incurred and payable, excluding current operating lease liabilities, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued Expenses And Other Current Liabilities Excluding Current Operating Lease Liabilities Accrued expenses and other current liabilities Accrued expenses and other current liabilities Operating Lease, Liability, Current Operating lease liabilities Liabilities, Current Total current liabilities Long-term Debt, Excluding Current Maturities Long-term debt, net of discount Other Liabilities, Noncurrent Other long-term liabilities Operating Lease, Liability, Noncurrent Operating lease liabilities, net of current portion Liabilities Total liabilities Commitments and Contingencies. Commitments and contingencies (see Note 9) Stockholders' Equity Attributable to Parent [Abstract] Stockholders' equity: Preferred Stock, Value, Issued Preferred stock, $0.001 par value; 10,000,000 shares authorized at March 31, 2022 and December 31, 2021; no shares issued or outstanding at March 31, 2022 and December 31, 2021 Common Stock, Value, Issued Common stock, $0.001 par value; 150,000,000 shares authorized at March 31, 2022 and December 31, 2021; 90,186,626 and 90,063,770 shares issued and outstanding at March 31, 2022 and December 31, 2021, respectively Additional Paid in Capital Additional paid-in capital Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive income Retained Earnings (Accumulated Deficit) Accumulated deficit Stockholders' Equity Attributable to Parent Balances at End of period Balances at Beginning of period Total stockholders' equity Liabilities and Equity Total liabilities and stockholders' equity Preferred Stock, Par or Stated Value Per Share Preferred stock, par value (in dollars per share) Preferred Stock, Shares Authorized Preferred stock, share authorized (in shares) Preferred Stock, Shares Issued Preferred stock, shares issued (in shares) Preferred Stock, Shares Outstanding Preferred stock, shares outstanding (in shares) Common Stock, Par or Stated Value Per Share Common stock, par value (in dollars per share) Common Stock, Shares Authorized Common stock, share authorized (in shares) Common stock, authorized (in shares) Common Stock, Shares, Issued Common stock, shares issued (in shares) Common Stock, Shares, Outstanding Common stock, shares outstanding (in shares) CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS Operating Expenses [Abstract] Operating expenses: Research and Development Expense Research and development General and Administrative Expense General and administrative Operating Expenses Total operating expenses Operating Income (Loss) Loss from operations Nonoperating Income (Expense) [Abstract] Other income (expense): Investment Income, Interest Interest income Interest Expense Interest expense Other Nonoperating Income (Expense) Other income, net Nonoperating Income (Expense) Total other income (expense), net Net Income (Loss) Attributable to Parent Net Loss Net loss Net loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract] Comprehensive loss: Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Other comprehensive income (loss): Other Comprehensive Income (Loss), Securities, Available-for-Sale, Unrealized Holding Gain (Loss) Arising During Period, after Tax Unrealized (losses) on investments, net of tax of $0 Comprehensive Income (Loss), Net of Tax, Attributable to Parent Comprehensive loss Other Comprehensive Income (Loss), Securities, Available-for-Sale, Unrealized Holding Gain (Loss) Arising During Period, Tax Unrealized gains (losses) on investments, tax CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS Cash flows from operating activities: Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net loss Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Share-based Compensation Stock-based compensation expense Depreciation, Depletion and Amortization Depreciation and amortization expense Investment Income, Net, Amortization of Discount and Premium Amortization (accretion) of premium (discount) on investments Non-Cash Interest Expenses Non-cash interest expense Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other current assets The increase (decrease) during the reporting period in the value of operating lease, right-of-use-asset. Increase Decrease, Operating Lease, Right Of Use Asset Operating lease, right-of-use-asset Increase (Decrease) in Accounts Payable Accounts payable The increase (decrease) during the reporting period in the amounts of accrued expenses and other current liabilities. Increase (Decrease) in Accrued Expenses and Other Current Liabilities Accrued expenses and other current liabilities Increase (Decrease) in Other Noncurrent Liabilities Other long-term liabilities The increase (decrease) during the reporting period in the value of operating lease liabilities. Increase Decrease, Operating Lease Liabilities Operating lease liabilities Net Cash Provided by (Used in) Operating Activities Net cash used in operating activities Net Cash Provided by (Used in) Investing Activities [Abstract] Cash flows from investing activities: Payments to Acquire Property, Plant, and Equipment Purchases of property, plant and equipment Payments to Acquire Investments Purchases of investments Proceeds from Sale, Maturity and Collection of Investments Sales and maturities of investments Net Cash Provided by (Used in) Investing Activities Net cash provided by (used in) investing activities Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows from financing activities: Proceeds from Issuance of Common Stock Proceeds from underwritten public offering of common stock, net of commissions and underwriting discounts Net proceeds after deducting underwriting discounts and commissions Proceeds from Stock Options Exercised Proceeds from issuance of common stock upon exercise of stock options Net Cash Provided by (Used in) Financing Activities Net cash provided by financing activities Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Net increase (decrease) in cash, cash equivalents and restricted cash Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents Cash, cash equivalents and restricted cash at end of period Cash, cash equivalents and restricted cash at beginning of period Cash, cash equivalents and restricted cash Supplemental Cash Flow Information [Abstract] Supplemental cash flow information: Interest Paid, Excluding Capitalized Interest, Operating Activities Cash paid for interest Operating Lease, Payments Cash paid for leases Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract] Supplemental disclosure of non-cash investing and financing information: Capital Expenditures Incurred but Not yet Paid Purchases of property, plant and equipment included in accounts payable or accrued expenses The amount of deferred offering cost included in accounts payable and accrued expenses. Deferred Offering Costs Included in Accounts Payable and Accrued Expenses Offering costs included in accounts payable and accrued expenses CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY Equity Components [Axis] Equity Component [Domain] Common stock Additional paid-in capital Accumulated other comprehensive income Accumulated deficit Shares, Outstanding Balances at End of period (in shares) Balances at Beginning of period (in shares) Stock Issued During Period, Value, New Issues Issuance of common stock from public offering, net of commissions, underwriting discounts and offering costs of $800 Stock Issued During Period, Shares, New Issues Shares issued (in shares) Issuance of common stock from public offering, net of commissions, underwriting discounts and offering costs (in shares) Stock Issued During Period, Value, Stock Options Exercised Issuance of common stock upon exercise of stock options Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period Exercised Issuance of common stock upon exercise of stock options (in shares) Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Vested in Period Vesting of restricted stock units Adjustments to Additional Paid in Capital, Share-based Compensation, Requisite Service Period Recognition Stock-based compensation expense Unrealized Gain (Loss) on Investments Unrealized gains (losses) on investments Nature of the Business and Basis of Presentation Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block] Nature of the Business and Basis of Presentation Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Investments and Fair Value of Financial Assets and Liabilities Fair Value Disclosures [Text Block] Investments and Fair Value of Financial Assets and Liabilities Property, Plant and Equipment, Net. Property, Plant and Equipment Disclosure [Text Block] Property, Plant and Equipment, Net Accrued Expenses and Other Current Liabilities Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block] Accrued Expenses and Other Current Liabilities Debt Debt Disclosure [Text Block] Debt Equity Stockholders' Equity Note Disclosure [Text Block] Equity Stock-Based Compensation Disclosure of Compensation Related Costs, Share-based Payments [Text Block] Stock-Based Compensation Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Commitments and Contingencies Net Loss per Share Earnings Per Share [Text Block] Net Loss per Share Disclosure of accounting policy for unaudited interim financial information. Unaudited Interim Financial Information [Policy Text Block] Unaudited Interim Financial Information Concentration Risk, Credit Risk, Policy [Policy Text Block] Concentrations of Credit Risk and of Significant Suppliers Cash and Cash Equivalents, Policy [Policy Text Block] Cash Equivalents Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block] Restricted Cash Fair Value Measurement, Policy [Policy Text Block] Fair Value Measurements Investment, Policy [Policy Text Block] Investments Lessee, Leases [Policy Text Block] Leases Investment [Table Text Block] Schedule of investments by security type Schedule of Fair Value, Assets and Liabilities Measured on Recurring Basis [Table Text Block] Schedule of financial assets and liabilities measured at fair value on a recurring basis Property, Plant and Equipment [Table Text Block] Schedule of property, plant and equipment, Net Tabular disclosure of the components of accrued liabilities and other current liabilities. Schedule of Accrued Liabilities and Other Current Liabilities [Table Text Block] Schedule of accrued expenses and other current liabilities Schedule of Maturities of Long-term Debt [Table Text Block] Schedule of estimated future principal payments due Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Fair value of stock-based awards granted to employees, directors, and, in 2018, non-employees, subsequent to the adoption of ASU 2018-07 Schedule of Compensation Cost for Share-based Payment Arrangements, Allocation of Share-based Compensation Costs by Plan [Table Text Block] Schedule of allocation of share based compensation Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Schedule of calculation of basic and diluted net loss per share attributable to common stockholders Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Schedule of dilutive securities excluded from computations of diluted weighted average shares outstanding Subsidiary or Equity Method Investee, Sale of Stock by Subsidiary or Equity Investee [Table] Sale of Stock [Axis] Sale of Stock [Domain] IPO Represents information related to an unwritten public offering. Offering Overallotment Subsidiary, Sale of Stock Nature of the business and basis of presentation Equity Proceeds from Issuance or Sale of Equity [Abstract] Sale of Equity Proceeds from Issuance Initial Public Offering IPO Net proceeds after deducting underwriting discounts and commissions Number of common stock issued on conversion Conversion of redeemable convertible preferred stock to common stock (in shares) Letters of Credit Outstanding, Amount Letters of credit Restricted Cash, Current, Asset, Statement of Financial Position [Extensible List] Current restricted cash included in prepaid expense and other current assets Restricted Cash Restricted cash Fair Value, by Balance Sheet Grouping [Table] Measurement Frequency [Axis] Fair Value, Measurement Frequency [Domain] Recurring Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Domain] Level 1 Level 2 Financial Instrument [Axis] Financial Instruments [Domain]