CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Operating expenses:
Research and development	$ 38,299	$ 27,677
General and administrative	12,563	13,240
Total operating expenses	50,862	40,917
Loss from operations	(50,862)	(40,917)
Other income (expense):
Interest income	48	26
Interest expense	(1,629)	(1,748)
Other income, net	31	309
Total other income (expense), net	(1,550)	(1,413)
Net loss	(52,412)	(42,330)
Comprehensive loss:
Net loss	(52,412)	(42,330)
Other comprehensive income (loss):
Unrealized (losses) on investments, net of tax of $0	(57)	3
Comprehensive loss	$ (52,469)	$ (42,327)