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Selected Quarterly Financial Data (Unaudited) (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Statements of Operations Data:                      
Total operating expenses $ 45,428 $ 48,482 $ 41,285 $ 34,406 $ 29,122 $ 27,554 $ 20,384 $ 14,603 $ 169,601 $ 91,663 $ 43,264
Loss from operations (45,428) (48,482) (41,285) (34,406) (29,122) (27,554) (20,384) (14,603) (169,601) (91,663) (43,264)
Net loss attributable to common stockholders $ (44,472) $ (47,015) $ (39,390) $ (32,581) $ (27,183) $ (26,362) $ (21,239) $ (14,411) $ (163,458) $ (89,195) $ (44,503)
Net loss per share attributable to common stockholders, basic and diluted $ (0.56) $ (0.59) $ (0.50) $ (0.42) $ (0.35) $ (0.42) $ (2.43) $ (1.72) $ (2.08) $ (2.27) $ (5.55)