<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:com="http://www.sec.gov/edgar/common">
<headerData>
<submissionType>144</submissionType>
<filerInfo>
<filer>
<filerCredentials>
<cik>0001704268</cik>
<ccc>XXXXXXXX</ccc>
</filerCredentials>
</filer>
<liveTestFlag>LIVE</liveTestFlag>



</filerInfo>
</headerData>
<formData>
<issuerInfo>
<issuerCik>0001709048</issuerCik>
<issuerName>GLOBALFOUNDRIES Inc.</issuerName>
<secFileNumber>001-40974</secFileNumber>
<issuerAddress>
<com:street1>400 Stonebreak Road Extension</com:street1>
<com:city>Malta</com:city>
<com:stateOrCountry>NY</com:stateOrCountry>
<com:zipCode>12020</com:zipCode>
</issuerAddress>
<issuerContactPhone>(518) 305-9013</issuerContactPhone>
<nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>Mubadala Technology Investment Company</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
<relationshipsToIssuer>
<relationshipToIssuer>Affiliate</relationshipToIssuer>
</relationshipsToIssuer>
</issuerInfo>
<securitiesInformation>
<securitiesClassTitle>Ordinary shares, par value US$0.02 per share</securitiesClassTitle>
<brokerOrMarketmakerDetails>
<name>Morgan Stanley &amp; Co. LLC</name>
<address>
<com:street1>1585 Broadway</com:street1>
<com:city>New York</com:city>
<com:stateOrCountry>NY</com:stateOrCountry>
<com:zipCode>10036</com:zipCode>
</address>
</brokerOrMarketmakerDetails>
<noOfUnitsSold>22000000</noOfUnitsSold>
<aggregateMarketValue>1979120000</aggregateMarketValue>
<noOfUnitsOutstanding>548416440</noOfUnitsOutstanding>
<approxSaleDate>05/26/2026</approxSaleDate>
<securitiesExchangeName>Nasdaq</securitiesExchangeName>
</securitiesInformation>
<securitiesToBeSold>
<securitiesClassTitle>Ordinary shares, par value US$0.02 per share</securitiesClassTitle>
<acquiredDate>10/27/2021</acquiredDate>
<natureOfAcquisitionTransaction>Shares acquired prior to the Issuer's initial public offering</natureOfAcquisitionTransaction>
<nameOfPersonfromWhomAcquired>The Issuer</nameOfPersonfromWhomAcquired>
<isGiftTransaction>N</isGiftTransaction>
<amountOfSecuritiesAcquired>378273074</amountOfSecuritiesAcquired>
<paymentDate>10/27/2021</paymentDate>
<natureOfPayment>See Nature of Acquisition Transaction</natureOfPayment>
</securitiesToBeSold>
<nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
<securitiesSoldInPast3Months>
<sellerDetails>
<name>Mubadala Technology Investment Company</name>
<address>
<com:street1>Maples Corporate Services Limited</com:street1>
<com:street2>PO Box 309, Ugland House</com:street2>
<com:city>Grand Cayman</com:city>
<com:stateOrCountry>E9</com:stateOrCountry>
<com:zipCode>KY1-1104</com:zipCode>
</address>
</sellerDetails>
<securitiesClassTitle>Ordinary shares, par value US$0.02 per share</securitiesClassTitle>
<saleDate>03/13/2026</saleDate>
<amountOfSecuritiesSold>28813857</amountOfSecuritiesSold>
<grossProceeds>1176901989.17</grossProceeds>
</securitiesSoldInPast3Months>
<remarks>The securities reported in Table II as sold in the past 3 months consist of shares sold pursuant to an effective registration statement and thus such sales are excluded from the volume limitation calculation, pursuant to Rule 144, pursuant to Rule 144(e)(3)(vii). The securities transaction reported in Table II includes the exercise by the underwriters on April 10, 2026 of their option to purchase 1,469,017 additional ordinary shares. The shares proposed to be sold are owned directly by Mubadala Technology Investment Company, a wholly-owned subsidiary of Mubadala Investment Company PJSC.</remarks>
<noticeSignature>
<noticeDate>05/26/2026</noticeDate>
<signature>/s/ Hernan Daniel Pellegrini</signature>
</noticeSignature>
</formData>
</edgarSubmission>
