X0306 4 2020-08-12 0 0001707502 Solid Biosciences Inc. SLDB 0001727460 Ganot Ilan C/O SOLID BIOSCIENCES INC. 141 PORTLAND STREET, 5TH FLOOR CAMBRIDGE MA 02139 1 1 0 0 CEO & President Common Stock 2020-08-12 4 M 0 800 A 3737 I Wife Common Stock 2020-08-13 4 S 0 299 2.4409 D 3483 I Wife Common Stock 1148007 D Common Stock 290914 I See Footnote Restricted Stock Units 2020-08-12 4 M 0 800 0.00 D Common Stock 800 0 I Wife Restricted Stock units convert into common stock on a one-for-one basis. This sale was made to cover withholding taxes following the vesting of the previously granted restricted stock units. Represents 1,087,376 shares held by Mr. Ganot as an individual, and 60,631 shares held by Mr. Ganot and Annie Ganot as joint tenants with right of survivorship. Represents 290,914 shares held by Adam Ganot and Annie Ganot, and their successors, as the trustees for the Ilan Ganot 2017 Irrevocable Trust dated March 3, 2017. On August 12, 2019, the reporting person's wife was granted 1,600 restricted stock units. The restricted stock units vested in two equal installments on February 12, 2020 and August 12, 2020. /s/ by Lynette Herscha as attorney-in-fact for Ilan Ganot 2020-08-14