X0306 4 2019-06-13 0 0001707502 Solid Biosciences Inc. SLDB 0001619841 Shah Rajeev M. C/O SOLID BIOSCIENCES INC. 141 PORTLAND STREET, 5TH FLOOR CAMBRIDGE MA 02139 1 0 0 0 Director Stock Option (Right to Buy) 5.26 2019-06-13 4 A 0 10000 0.00 A 2029-06-13 Common Stock 10000 10000 D This option was granted on June 13, 2019 and vests in full on the earlier to occur of the one-year anniversary of the grant date and immediately prior to the Issuer's next annual meeting of stockholders occurring after the grant date, and will vest automatically as to 100% of the unvested portion of such option upon specified change in control events. Under the Reporting Person's arrangement with RA Capital Management, LLC (the "Manager"), the Reporting Person holds the option for the benefit for the benefit of RA Capital Healthcare Fund, L.P. (the "Fund") and a separately managed account (the "Account"). The Reporting Person is obligated to turn over to the Manager any net cash or stock received upon exercise of the option, which will offset advisory fees owed by the Fund and Account to the Manager. The Reporting Person therefore disclaims beneficial ownership of the option and underlying common stock. /s/ Rajeev M Shah 2019-06-14