Collaborations - Summary of Changes in Balances of Company's Related Party Collaboration Receivables and Contract Liabilities (Detail) - Ultragenyx [Member] - Collaborative Arrangement, Transaction with Party to Collaborative Arrangement [Member] - Related Party [Member]	12 Months Ended
	Dec. 31, 2022 USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Related party collaboration receivables, Beginning balance	$ 110,000
Related party collaboration receivable, Additions	14,000
Related party collaboration receivable, Deductions	(124,000)
Related party collaboration receivables, Ending balance	0
Deferred revenue, Beginning balance	8,080,000
Deferred revenue, Deductions	$ (8,080,000)