Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Cash flows from operating activities:
Net loss	$ (50,420)	$ (35,595)
Adjustments to reconcile net loss to net cash used in operating activities:
Amortization of premium on available-for-sale securities	526	7
Equity-based compensation expense	4,426	6,542
Depreciation expense	1,431	1,453
Loss on disposal of property and equipment		3
Gain on termination of lease	(249)
Changes in operating assets and liabilities:
Prepaid expenses and other current and non-current assets	586	621
Accounts receivable - related party	110	(286)
Accounts payable	373	(318)
Accrued expenses and other current and non-current liabilities	8,229	(4,529)
Deferred revenue- related party, current and non-current	(8,080)	(6,364)
Net cash used in operating activities	(43,068)	(38,466)
Cash flows from investing activities:
Purchases of property and equipment	(1,320)	(384)
Proceeds from sale and maturities of available-for-sale securities	92,156
Purchases of available-for-sale securities	(112,688)	(48,368)
Net cash used in investing activities	(21,852)	(48,752)
Cash flows from financing activities:
Proceeds from issuance of common stock, net of issuance costs		134,878
Proceeds from exercise of warrants	22
Employee stock purchases and withholding	73
Proceeds from exercise of stock options		38
Net cash provided by financing activities	95	134,916
Net (decrease) increase in cash, cash equivalents and restricted cash	(64,825)	47,698
Cash, cash equivalents, and restricted cash at beginning of period	121,206	155,071
Cash, cash equivalents, and restricted cash at end of period	56,381	202,769
Supplemental disclosure of non-cash investing and financing activities:
Right-of-use assets obtained in exchange for operating lease liabilities	29,126
Decrease in right of use asset due to lease termination	(464)	(1,233)
Property and equipment included in accounts payable and accruals	$ 600	$ 47