In April 2022, the Company implemented changes to its corporate strategy to prioritize the advancement of its key programs, SGT-001 and SGT-003. In connection with the changes to corporate operations, the Company reduced headcount by approximately 35 percent. During the three and six months ended June 30, 2022, the Company recorded aggregate restructuring charges of $1,520 related to severance and other employee related costs. The Company does not expect to incur any additional significant costs associated with this restructuring. During the three and six months ended June 30, 2022, the Company paid $728 of the estimated restructuring charges. The Company expects the remaining accrued restructuring charges of $792 to be paid in the next six months.


	One-Time Employee Termination Benefits
Accrued restructuring charges as of December 31, 2021	$	—
Accrual recorded as a result of restructuring charges		1,520
Amounts paid during the period		(728	)
Accrued restructuring charges as of June 30, 2022	$	792