X0306 4 2020-09-14 0 0001513818 Aravive, Inc. ARAV 0001033409 ESHELMAN FREDRIC N C/O ARAVIVE, INC. RIVER OAKS TOWER, 3730 KIRBY DRIVE, SUITE 1200 HOUSTON TX 77098 1 0 0 0 0001706673 Eshelman Ventures, LLC C/O ARAVIVE, INC. RIVER OAKS TOWER 3730 KIRBY DRIVE, SUITE 1200 HOUSTON TX 77098 0 0 0 1 See Remarks Stock Option 5.63 2020-09-14 4 A 0 16029 0.00 A 2020-10-14 2030-09-13 Common Stock 16029 16029 D These options vest pro rata on a monthly basis commencing on October 14, 2020 for the next 12 months with full vesting, if not fully vested at such time, on the date of Aravive, Inc.'s next annual meeting of stockholders. Dr. Fredric Eshelman is a director of Aravive, Inc. and is the founder and principal of Eshelman Ventures, LLC. ESHELMAN VENTURES, LLC, By: /s/ Fredric N. Eshelman, Name: Fredric N. Eshelman, Title: Managing Member 2020-09-15 /s/ Fredric N. Eshelman 2020-09-15